Computational model for tumor response to adoptive cell transfer therapy [PDF]
One of the barriers to the development of effective adoptive cell transfer therapies (ACT), specifically for genetically engineered T-cell receptors (TCRs), and chimeric antigen receptor (CAR) T-cells, is target antigen heterogeneity. It is thought that intratumor heterogeneity is one of the leading determinants of therapeutic resistance and treatment ...
arxiv
Effectiveness of Narrowband Ultraviolet on Vitiligo: A Systematic Review
Background: Narrowband ultraviolet B (nb-UVB) is one of the most popular and effective modalities to treat vitiligo. Given the importance of nb-UBV, as well as its associations, this research searched the literature for answers on how to best treat ...
Ana Luisa Tenani Pereira da Costa+7 more
doaj +1 more source
Efficacy and safety of narrowband ultraviolet B phototherapy for prurigo nodularis: a tertiary center experience [PDF]
Background: Prurigo nodularis is a chronic pruritic dermatosis and narrowband-UVB (NB-UVB) phototherapy is considered an effective and safe treatment option in patients with multiple comorbidities. Objective: In this study, the authors aimed to evaluate
Esra Agaoglu+3 more
doaj +1 more source
Laser therapy in superficial morphea lesions – indications, limitations and therapeutic alternatives [PDF]
Morphea or localized scleroderma is an uncommon autoimmune and inflammatory disease which affects patients of any age. Even if morphea lesions present systemic symptoms as myalgias or arthritis, it is distinct from systemic sclerosis because it does not ...
Ardeleanu, Valeriu+4 more
core +1 more source
Xeroderma pigmentosum (XP) is defined by extreme sensitivity to sunlight, resulting in sunburn, pigment changes in the skin and a greatly elevated incidence of skin cancers.
Lehmann, Alan R+2 more
core +3 more sources
Effciency and safety of the use of long-wave UVA-1 phototherapy in treatment of psoriasis [PDF]
<p> </p><p> </p><p>The effectiveness of the long wavelength ultraviolet therapy (UVA-1) in complex treatment of patients with psoriasis has been studied during the research.
Bakulev A.L.+2 more
doaj
Treatment recommendations for psoriatic arthritis [PDF]
Objective: To develop comprehensive recommendations for the treatment of the various clinical manifestations of psoriatic arthritis (PsA) based on evidence obtained from a systematic review of the literature and from consensus opinion.
Boehncke, Wolf-Henning+14 more
core +2 more sources
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Optical and thermal effects in the neighborhood of the spherical layered nanoparticle of the "metallic core -- J-aggregate shell'' structure [PDF]
The relations for the polarizability of the metallic nanoparticles, coated with the shell of cyanine dyes, are obtained in the article. The frequency dependencies for light absorption and scattering efficiencies, the heating of the composite nanoparticle and the electric field amplification in its neighborhood are studied.
arxiv +1 more source
Photodynamic Therapy of Necrobiosis Lipoidica - A Multicenter Study of 18 Patients [PDF]
Background: Necrobiosis lipoidica (NL) is a granulomatous skin disease of unknown origin, and no reliably effective treatment option exists to handle this often disfiguring disease.
Arenberger, P.+4 more
core +1 more source