Results 51 to 60 of about 2,617,488 (303)

Upcoming Therapeutic Modalities for the Treatment of Keloids: An Update

open access: yesNepal Journal of Dermatology, Venereology & Leprology, 2019
Introduction: Keloids are benign dermal tumors that generally form by local fibroblast proliferation and excessive collagen production following skin trauma.
Uma Keyal, Anil Kumar Bhatta
doaj   +3 more sources

Methoxsalen-induced macular toxicity

open access: yesIndian Journal of Ophthalmology, 2017
Psoralen compounds such as methoxsalen are photosensitizer agents used in conjunction with ultraviolet A (UVA) radiation exposure as photochemotherapy (Psoralens and ultraviolet-A therapy [PUVA therapy]) for certain epidermal skin disorders such as ...
Aditya Maitray, Pukhraj Rishi
doaj   +1 more source

Photoadaptation of the skin during exposure to narrowband ultraviolet b radiation [PDF]

open access: yes, 2000
The aim of this study is to determine the rate at which UVB radiation takes effect in order to produce an effective regimen for treatment. Psoriasis, a chronic, proliferative, inflammatory disease that is under genetic and environmental control is the ...
Layton, Susan
core  

Update on Viral Gene Therapy Clinical Trials for Retinal Diseases [PDF]

open access: yes, 2022
In 2001, the first large animal was successfully treated with a gene therapy that restored its vision. Lancelot, the Briard dog that was treated, suffered from a human childhood blindness called Leber's congenital amaurosis type 2.
Cheng, Shun-Yun, Punzo, Claudio
core   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Ultraviolet A Is AnEfficient Therapy For Plane Warts

open access: yesDiyala Journal of Medicine, 2019
Background:Treatment ofplane warts presents a special therapeutic problem because their duration is long, and very resistant to many treatments. In addition they are usually located in cosmetically important areas, so therapy should be as mild as ...
AlaaAldeen Khorsheed Murad   +2 more
doaj   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Generalized syringotropic mycosis fungoides responsive to total skin electron beam therapy

open access: yesDermatologica Sinica, 2014
A case of syringotropic mycosis fungoides without internal organ involvement received total skin electron beam therapy (TSEBT) and evolved into poikilodermatous mycosis fungoides.
Pei-Hsuan Lu   +4 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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