Results 71 to 80 of about 4,844,377 (373)

A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy. [PDF]

open access: yes, 2015
Although recent methods for the engineering of antibody-drug conjugates (ADCs) have gone some way to addressing the challenging issues of ADC construction, significant hurdles still remain.
Caddick, S   +5 more
core   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Methoxsalen-induced macular toxicity

open access: yesIndian Journal of Ophthalmology, 2017
Psoralen compounds such as methoxsalen are photosensitizer agents used in conjunction with ultraviolet A (UVA) radiation exposure as photochemotherapy (Psoralens and ultraviolet-A therapy [PUVA therapy]) for certain epidermal skin disorders such as ...
Aditya Maitray, Pukhraj Rishi
doaj   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

Generalized syringotropic mycosis fungoides responsive to total skin electron beam therapy

open access: yesDermatologica Sinica, 2014
A case of syringotropic mycosis fungoides without internal organ involvement received total skin electron beam therapy (TSEBT) and evolved into poikilodermatous mycosis fungoides.
Pei-Hsuan Lu   +4 more
doaj   +1 more source

Oxidative Stress and Photodynamic Therapy of Skin Cancers: Mechanisms, Challenges and Promising Developments

open access: yesAntioxidants, 2020
Ultraviolet radiation is one of the most pervasive environmental interactions with humans. Chronic ultraviolet irradiation increases the danger of skin carcinogenesis.
Alessandro Allegra   +4 more
doaj   +1 more source

Ultraviolet A Is AnEfficient Therapy For Plane Warts

open access: yesDiyala Journal of Medicine, 2019
Background:Treatment ofplane warts presents a special therapeutic problem because their duration is long, and very resistant to many treatments. In addition they are usually located in cosmetically important areas, so therapy should be as mild as ...
AlaaAldeen Khorsheed Murad   +2 more
doaj   +2 more sources

Incidence and Risk Factors Associated with a Second Squamous Cell Carcinoma or Basal Cell Carcinoma in Psoralen + Ultraviolet A Light-treated Psoriasis Patients [PDF]

open access: yes, 2002
Psoralen + ultraviolet A-treated psoriasis patients are at increased risk for squamous cell carcinomas and basal cell carcinomas; however, the incidence and risk factors associated with second squamous cell carcinomas and basal cell carcinomas in this ...
Katz, Kenneth A.   +2 more
core   +1 more source

Association of Higher Levels of High‐Sensitivity C‐Reactive Protein With Future Development of Psoriatic Arthritis in Psoriasis: A Prospective Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to assess whether high‐sensitivity C‐reactive protein (hsCRP) levels could predict the development of psoriatic arthritis (PsA) in patients with psoriasis. Methods We analyzed data from a prospective cohort of patients with psoriasis without PsA at enrollment.
Lihi Eder   +5 more
wiley   +1 more source

TREatment of ATopic eczema (TREAT) Registry Taskforce: consensus on how and when to measure the core dataset for atopic eczema treatment research registries. [PDF]

open access: yes, 2019
BackgroundComparative, real-life and long-term evidence on the effectiveness and safety of phototherapy and systemic therapy in moderate-to-severe atopic eczema (AE) is limited.
Apfelbacher, CJ   +17 more
core  

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