Results 31 to 40 of about 398 (162)

Management of Kashtartava (Dysmenorrhea) with Vishwadi Kwatha: An Open Labelled Single -Arm Clinical Trial [PDF]

open access: yes
Introduction: Kashtartava (Dysmenorrhea) is a commonly reported menstrual disorder which affects the working ability and quality of life of the woman. Due to in discreet diet and lifestyle, young women are more liable to get afflicted with this disorder ...
Anagha Sivanandan, Metaliya Denish R.
core   +2 more sources

Development of a Photoactivatable Reporter to Perform Temporally Controlled Measurements of Enzyme Activity in Single Cells [PDF]

open access: yes, 2021
Synthetic peptide reporters are useful biochemical tools in the field of biomedicalresearch with diverse applications ranging from use as substrates for recombinant enzymes, celllysates, bulk live cells, and even single mammalian cells.
Anttila, Matthew Michael
core   +2 more sources

Phasentrennung von Nukleinsäuren: Mechanismen, Eigenschaften und Anwendungen

open access: yesAngewandte Chemie, EarlyView.
Jüngste Entdeckungen zeigen, dass einzelsträngige langkettige Nukleinsäuren temperaturinduziert phasentrennen und dabei mikrometergroße Kondensate bilden. Dieser Minireview fasst das aktuelle mechanistische Verständnis dieses Phänomens zusammen, beschreibt Strategien zur gezielten Kontrolle der physikalischen und chemischen Eigenschaften der Kondensate
Weixiang Chen   +2 more
wiley   +1 more source

Somatostatin Regulates the Extracellular Regulated Kinase Cascade of Human Rheumatoid Arthritis Synoviocytes [PDF]

open access: yes, 2006
Somatostatin (SRIF, somatotropin release inhibitory factor) is a ubiquitously expressed neuropeptide, interacting with cells via five SRIF receptor subtypes (sst.-sst.), belonging to the guanine nucleotide binding protein-coupled receptor (GPCR ...
West, Frances Mae
core   +3 more sources

Phase Separation of Nucleic Acids: Mechanisms, Properties, and Applications

open access: yesAngewandte Chemie International Edition, EarlyView.
Recent discoveries have shown that single‐stranded long‐chain nucleic acids can undergo temperature‐induced phase separation, enabling formation of micrometer‐sized condensates. This Minireview discusses the current mechanistic understanding of this phenomenon, highlights strategies for controlling the physical and chemical properties of these ...
Weixiang Chen   +2 more
wiley   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani   +3 more
wiley   +1 more source

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

open access: yesNew Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov   +16 more
wiley   +1 more source

Introducing the Cis‐2,3‐Bis(trifluoromethyl)cyclopropyl Chemotype: Late‐Stage Installation and Stereoelectronic Properties

open access: yesChemistryEurope, Volume 4, Issue 2, February 2026.
The cis‐2,3‐bis(trifluoromethyl)cyclopropyl chemotype is introduced. The steric demand of this motif is intermediate between that of the heptafluoroisopropyl and prefluorotertbutyl groups; yet, it induces significantly less lipophilicity than these due to its facial polarity.
Daniel Gaviña   +5 more
wiley   +1 more source

Chip-scale bioassays based on surface-enhanced Raman scattering: fundamentals and applications [PDF]

open access: yes, 2005
This work explores the development and application of chip-scale bioassays based on surface-enhanced Raman scattering (SERS) for high throughput and high sensitivity analysis of biomolecules;The size effect of gold nanoparticles on the intensity of SERS ...
Park, Hye-Young
core   +3 more sources

Controlled Dual Activation of Rhenium(I) Photosensitizers and Profluorophores/Prodrugs via a Dissociative Bioorthogonal Tetrazine–Isonitrile Reaction

open access: yesAngewandte Chemie, Volume 137, Issue 50, December 8, 2025.
Rhenium(I) tetrazylmethyl complexes serve as phosphorogenic bioorthogonal reagents, releasing luminescent and photocytotoxic rhenium(I) 3‐hydroxypyridine complexes and functional payloads upon reaction with 3‐isocyanopropyl derivatives. Their selective lysosomal accumulation in cancer cells and enhanced singlet oxygen photosensitization in acidic ...
Eunice Chiu‐Lam Mak   +2 more
wiley   +2 more sources

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