Results 41 to 50 of about 398 (162)

Uncovering the Key Factors Influencing Phytochemical and Phytopharmacological Properties During Medicinal Plant Processing

open access: yeseFood, Volume 7, Issue 1, February 2026.
From farm to pharma, this review details the engineering of quality in medicinal plants through a science‐driven approach: it first elucidates how genetic and environmental factors inscribe the plant's phytochemical and phytopharmacological profile before harvest, and then dissects the postharvest techniques and technologies—chemical and thermal pre ...
Elyas Aryakia
wiley   +1 more source

Somatostatin Regulates Intracellular Signaling in Human Bronchial Smooth Muscle Cells [PDF]

open access: yes, 2005
Somatostatin (somatotropin release inhibitory factor; SRIF), is an endogenous peptide family that controls cellular secretion and proliferation. While SRIF\u27s cognate receptors and associated actions have been clearly identified in a range of tissues ...
Alfonzo, Michael J.
core   +1 more source

Integrated green extraction of phenolic compounds and fermentable sugars from grapefruit peel using ultrasound and enzymatic hydrolysis

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 3, Page 1839-1851, February 2026.
Abstract BACKGROUND Valorizing sugar‐rich food waste in biorefineries offers a sustainable route to bio‐based products. Grapefruit peel (GP), representing about 50% of the fruit's weight, is rich in sugars (soluble and insoluble) and polyphenols such as flavonoids.
María del Prado García‐Aparicio   +2 more
wiley   +1 more source

A High Throughput Assay to Identify Small Molecule Modulators of Prostatic Acid Phosphatase [PDF]

open access: yes
Prostatic acid phosphatase (PAP) is expressed in nociceptive neurons and functions as an ectonucleotidase. Injection of the secretory isoform of PAP has potent antinociceptive effects in mouse models of chronic pain.
Larsen, Rylan S   +2 more
core   +2 more sources

Synthesis of optically-labelled vanadyl complexes and their evaluation as protein tyrosine phosphatase inhibitors and intracellular probes [PDF]

open access: yes, 2016
Cysteine based phosphatases (CBPs) are a diverse family of enzymes that act to remove the phosphate group from proteins, phosphatidylinositols and other biomolecules, thereby counteracting the effects of kinases.
Collins, Juliet Claire
core   +1 more source

Heat drastically alters floral color and pigment composition without affecting flower conspicuousness

open access: yesAmerican Journal of Botany, Volume 113, Issue 1, January 2026.
Abstract Premise Floral pigments primarily serve to attract pollinators through color display and also contribute to protection against environmental stress. Although pigment composition can be plastically altered under stress, its impact on pollinator color perception remains poorly understood.
Eduardo Narbona   +6 more
wiley   +1 more source

Nutritional Content, Phytochemical Composition, and Physicochemical Properties of Different Quinoa (Chenopodium quinoa Willd.) Seed Varieties

open access: yesCereal Chemistry, Volume 103, Issue 1, Page 93-109, January/February 2026.
ABSTRACT Background and Objectives Quinoa (Chenopodium quinoa Willd.) is a pseudocereal with documented benefits for human health. The macronutrient composition and phytochemical content of the grain are known to vary depending on the variety and the growing location.
Vassilios Raikos   +7 more
wiley   +1 more source

Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds

open access: yesChemMedChem, Volume 21, Issue 2, January 2026.
Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley   +1 more source

Artificial Intelligence‐Based In Silico Evaluation of the Pharmacological Potential and In Vitro Anti‐Malignancy Effect in the Human Glioblastoma Cell Line of the Hydrate of the Coumarin Compound Meranzin Originating From the Edible Macroalga (Bangia fuscopurpurea)

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
In U87 cells, meranzin hydrate showed cytotoxicity (MIC = 50 μM) and anti‐invasion activity (IC50 = 33.12 μM) but had no inhibitory effect on colony formation. It also suppressed the cancer stem cell property of sphere formation (IC50 = 21.43 μM). In silico analysis indicated that meranzin hydrate may downregulate the protein expression of ALDH1A1 and ...
Shi‐Ying Huang   +10 more
wiley   +1 more source

Dual‐Pathway Defense: Ultramicro‐Pulverised Powder of Polygonum chinense L. and Atractylodes rhizome (PAUP) Rescues Broilers From E. coli‐Triggered Liver Injury Through Modulation of Oxidative Stress and Inflammation

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
Reduced Antibiotic residues and resistance concerns: Offers a potential natural alternative to antibiotics for combating E. coli infections in poultry. Provided safer poultry food products: By enhancing liver function, restoring weight gain, and improving feed efficiency, PAUP supports the production of healthier chickens, ultimately contributing to ...
Jia‐Ci Cai   +11 more
wiley   +1 more source

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