Results 41 to 50 of about 378,881 (349)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Comparative diagnostic performance of imaging modalities in chronic pancreatitis: a systematic review and Bayesian network meta-analysis

BMC Medical Imaging
Purpose We aimed to perform a Bayesian network meta-analysis to assess the comparative diagnostic performance of different imaging modalities in chronic pancreatitis(CP).
Ping Yu, Xujia Zhou, Li Yue, Ling Zhang, Yuan Zhou, Fei Jiang   +5 more
doaj   +1 more source

IL2rg Cytokines Enhance Umbilical Cord Blood CD34+ Cells Differentiation to T Cells [PDF]

Advanced Pharmaceutical Bulletin, 2015
Purpose: Umbilical cord blood (UCB) is an alternative source of hematopoietic stem cell (HSC) transplantation for the treatment of patients with leukemia if matched donor is not available.
Zeynab Aliyari, Sara Soleimanirad, Manizheh Sayyah Melli, Hamid Tayefi Nasrabadi, Hojjatollah Nozad Charoudeh   +4 more
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

ABI3BP promotes renal aging through Klotho-mediated ferroptosis

Journal of Translational Medicine
The aging process of the kidneys is accompanied with several structural diseases. Abnormal fiber formation disrupts the balance of kidney structure and function, causing to end-stage renal disease and subsequent renal failure.
Ren Ji, Lin Wei, Yuxin Zan, Xiao Li, Shinan Ma, Liming Ma, Xiju He, Li Wang, Yan Ding   +8 more
doaj   +1 more source

Uterine and umbilical artery doppler in women with pre-eclampsia and their pregnancy outcomes

Nigerian Postgraduate Medical Journal, 2019
Background: Pre-eclampsia (PE) is an important public health menace in both developed and developing countries with high maternal and perinatal morbidity and mortality globally.
Ademola Joseph Adekanmi, Adebola Roberts, Janet Adetinuke Akinmoladun, Abiodun Oludotun Adeyinka   +3 more
doaj   +1 more source

[Artículo traducido] Análisis comparativo de los nódulos umbilicales en pacientes masculinos y femeninos: un estudio retrospectivo de 20 años

Actas Dermo-Sifiliográficas, 2022
Resumen: Antecedentes y objetivo: Se sabe que en el ombligo se presentan metástasis de neoplasias de diversos órganos viscerales. Es imperativo el diagnóstico preciso y correcto de las lesiones umbilicales, ya que la caracterización metastásica implica ...
N.T. Onyishi, O.C. Okafor
doaj   +1 more source

Umbilical Artery Doppler Indices in Hypertensive Disorders of Pregnancy: Impact on Fetal Outcomes [PDF]

, 2023
Kalyani S Mahajan, Deepika Dewani, Sakshi Duragkar   +2 more
openalex   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source