Results 51 to 60 of about 282,777 (307)
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti +4 more
wiley +1 more source
Abstract Pilonidal sinus of the umbilicus is rarely reported, and there are only 17 reported cases. On reviewing the records from Jordan University Hospital, 24 patients who were treated surgically for a discharging umbilical sinus were found.
A S, Sroujieh, A, Dawoud
openaire +2 more sources
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan +17 more
wiley +1 more source
Mesenchymal Stem Cell - Derived Exosomes: New Opportunity i n Cell - Free Therapy
Mesenchymal stromal/stem cells (MSCs) are involved in tissue homeostasis through direct cell - to - cell interaction, as well as secretion of soluble factors. Exosomes are the sort of soluble biological mediators that obtained from MSCs cultured media in
Davod Pashoutan Sarvar +2 more
doaj +1 more source
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng +15 more
wiley +1 more source
Design of Steel Tube Element in Subsea Umbilical
In the design of umbilical for subsea production system, the structural stress of steel tube element under various loads should be calculated and the wall thickness of steel tube should be analyzed. According to the requirements of the specification, the
Li Bo, Qu Yan, Guo Hong, Guo Jiangyan
doaj
ABI3BP promotes renal aging through Klotho-mediated ferroptosis
The aging process of the kidneys is accompanied with several structural diseases. Abnormal fiber formation disrupts the balance of kidney structure and function, causing to end-stage renal disease and subsequent renal failure.
Ren Ji +8 more
doaj +1 more source
Primary umbilical endometriosis: Case report with literature review
Villars nodule, also known as umbilical endometriosis, is a rare umbilical disorder, usually affecting women of child bearing age. Endometriosis is a functional endometrial tissue found outside the uterine cavity, which affects the umbilicus in 0.5–1% of
Sara A Al-Quorain, Tariq A Al-Yahya
doaj +1 more source
Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez +16 more
wiley +1 more source

