Results 111 to 120 of about 52,076 (287)

Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress. [PDF]

, 2017
Sirtuin1 (Sirt1) is a class III histone deacetylase that regulates a variety of physiological processes, including endothelial function. Caveolin1 (Cav1) is also an important determinant of endothelial function. We asked if Sirt1 governs endothelial Cav1
Gabani, Mohanad, Irani, Kaikobad, Jacobs, Julia S, Kassan, Adam, Kassan, Modar, Kim, Young-Rae, Kumar, Santosh, Li, Qiuxia, Liu, Jing, Patel, Hemal H, Vikram, Ajit   +10 more
core   +3 more sources

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12‐Related Developmental Disorders

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source

Influência do Tabagismo no Sistema Vascular Materno-fetal: estudo com Dopplervelocimetria Effect of Cigarette Smoking on Maternal-fetal Blood Flow: Doppler Velocimetry Study

Revista Brasileira de Ginecologia e Obstetrícia, 2000
Objetivo: avaliar a influência do tabagismo materno na dinâmica vascular materno-fetal, por meio da dopplervelocimetria obstétrica das artérias uterinas, umbilical e cerebral média. Métodos: estudo prospectivo em 42 gestantes saudáveis, sendo 20 fumantes
Gilberto Rodrigues Pinto, Clovis Botelho
doaj   +1 more source

Characterization and profiling of immunomodulatory genes of equine mesenchymal stromal cells from non-invasive sources [PDF]

, 2014
Introduction: Mesenchymal stromal cells (MSCs) have been extensively studied for their promising capabilities in regenerative medicine. Although bone marrow is the best-known source for isolating equine MSCs, non-invasive alternative sources such as ...
De Schauwer, Catharina, Goossens, Karen, Govaere, Jan, Hoogewijs, Maarten, Meyer, Evelyne, Piepers, Sofie, Smits, Katrien, Van de Walle, Gerlinde, Van Soom, Ann   +8 more
core   +2 more sources

Novel MYL1 Intron Variant With Expanded Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Congenital myopathy‐14 (CMYO14) is an ultrarare autosomal recessive disorder caused by biallelic variants in MYL1, with only four patients reported to date. We describe what is likely the fifth reported patient, a neonate with severe hypotonia, respiratory insufficiency, and skeletal anomalies showing distinct histological changes of skeletal ...
Maria Barington, Marie Balslev‐Harder, Thomas Krag, Thomas van Overeem Hansen, Camilla Bernt Wulff, Ulrik Lausten‐Thomsen, Tina Duelund Hjortshøj, Elsebet Østergaard   +7 more
wiley   +1 more source

Morphological aspects of buffaloes (Bubalus bubalis) umbilical cord Aspectos Morfológicos do cordão umbilical de búfalos (Bubalus bubalis)

Pesquisa Veterinária Brasileira, 2009
Buffalo is an important livestock resource, with a great participation in agricultural systems, providing milk, meat, and work power. Umbilical cord is responsible for maternal-fetal nutrients exchange during pregnancy, and its alterations can compromise
Guilherme J. Ferreira, Érika Branco, Rosa Cabral, Guilherme B. Gregores, Emerson T. Fioretto, Ana Rita de Lima, Carlos Alberto P. Sarmento, Maria Angelica Miglino, Ana F. Carvalho   +8 more
doaj   +1 more source

Doppler Ultrasound of the Fetal Descending Aorta: An Objective Tool to Assess Placental Blood Flow Resistance in Pregnancies With Discordant Umbilical Arteries. [PDF]

J Ultrasound Med, 2022
Cahill LS, Mercer GV, Jagota D, Ravi Chandran A, Milligan N, Shinar S, Whitehead CL, Hobson SR, Serghides L, Parks WT, Macgowan CK, Kingdom JC, Sled JG, Baschat AA.   +13 more
europepmc   +1 more source

Distribution of endothelial cell protein C/activated protein C receptor (EPCR) during mouse embryo development. [PDF]

, 2002
The endothelial cell protein C receptor (EPCR) augments protein C activation by the thrombomodulin.thrombin complex. Deletion of the EPCR gene in mice has been reported to lead to embryonic lethality before embryonic day 10 (E10.0). To identify potential
Crawley, JT, Esmon, CT, Ferrell, G, Gu, JM   +3 more
core  

Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen, Li Gao, Xu Han, Yunyun Cao, Lanlan Zhang, Yi Wu, Xinrong Zhao, Wenjing Hu, Ruiyu Ma, Renyi Hua, Niu Li, Yanlin Wang, Jian Wang, Shuyuan Li   +13 more
wiley   +1 more source

Foramen Ovale Pulsatility Index as an Early Affected Doppler Study among Abnormal Growth Fetuses: A Recent Insight for Practice Based on a Prospective Study [PDF]

Iranian Journal of Medical Sciences
Background: Routine Doppler study is a common tool for early diagnosis of Fetal Growth Restriction (FGR) and Small for Gestational Age (SGA) patients.
Azam Faraji, Fereshteh Gharibpour, Niloofar Namazi, Ali Mohammad Shakiba, Maryam Kasraeian, Nasrin Asadi, Homeira Vafaei, Marjan Zare, Khadijeh Bazrafshan, Zahra Oveisi   +9 more
doaj   +1 more source