Results 181 to 190 of about 52,076 (287)

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

open access: yesSmall Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto   +12 more
wiley   +1 more source

Angiogenic factors and fetal Doppler for predicting adverse pregnancy outcome in early‐onset small fetuses with and without pre‐eclampsia

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objectives To assess the predictive performance of angiogenic factors and fetal Doppler, alone and in combination, for composite adverse perinatal outcome (CAPO) in early‐onset small‐for‐gestational age (SGA) and fetal growth restriction (FGR), in cases both with and without pre‐eclampsia (PE), in order to evaluate the ability of these markers
E. Bonacina   +13 more
wiley   +1 more source

Pseudorandomised controlled trial of a novel navel barrier solution versus 10% iodine to protect navel and ear tag sites of neonatal lambs

open access: yesVeterinary Record, EarlyView.
Abstract Background During lambing, 10% iodine is often used to protect neonatal navel and ear tag sites. The evidence for its effectiveness is sparse. Recently, a specific navel barrier solution (NBS) was developed. Here, an in vivo field trial compared the two treatments. Methods Ten farms reported data from 6840 lambs. The navel and ear tag sites of
Fiona M. Lovatt   +3 more
wiley   +1 more source

Heat Stress and Placental Abruption: A Space–Time Stratified Case‐Crossover Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine whether heat stress, measured by wet bulb globe temperature (WBGT), a comprehensive heat stress index is associated with placental abruption within 7 days. Design A space–time‐stratified case‐crossover design. Setting All 11 regions in Japan during the warm season (June–September) from 2011 to 2020.
Shuhei Terada   +3 more
wiley   +1 more source

Foetal Cardiac Function in Early Labour and Intrapartum Outcomes: A Prospective Observational Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To assess foetal myocardial deformation in normo‐oxygenated foetuses in early labour and its relationship with intrapartum outcomes. Design Single centre prospective study. Setting Referral tertiary maternity unit. Population Uncomplicated singleton term pregnancies in early labour.
Andrea Dall'Asta   +7 more
wiley   +1 more source

De Novo RRAS2 Pathogenic Variant in a Fetus With Bilateral Radial Ray and Multisystem Anomalies

open access: yes
Prenatal Diagnosis, EarlyView.
Nicole R. Legro   +3 more
wiley   +1 more source

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