Results 41 to 50 of about 227,938 (286)

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Herniation of the appendix into the umbilical cord complicating umbilical vessel cannulation

Journal of Pediatric Surgery Case Reports, 2019
Umbilical catheters (UC) have become the most common way to access neonatal veins and arteries especially after the increasing the number of preterm newborns. Significant clinical complications have been reported with this increased usage of UC.
Mohammad Mahdi Khazravi, Marjan Joodi, Shiva Ghaderifar, Mehdi Fathi, Reza Nazarzade, Hossein Mohsenzade, Maryam Joudi   +6 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

Advanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris, Sangho Lee, Kalp Soni, Simon He, Matthew Huang, Dandan Chen, Dae Hoon Lee, Kyung Hee Kim, Seonggeon Cho, Laura Pencea, Divit Jain, Young‐Sup Yoon   +11 more
wiley   +1 more source

Histopathological characterisation of omphalitis in piglets

Acta Veterinaria Scandinavica
Background Antibiotic treatment of piglets after birth is commonly carried out due to concern for development of omphalitis leading to umbilical outpouchings and/or systemic infections.
Sophie Amalie Blirup-Plum, Henrik Elvang Jensen, Søren Saxmose Nielsen, Katrine Top Hartmann, Mette Sif Hansen, Ken Steen Pedersen, Inge Larsen, Jens Peter Nielsen, John Elmerdahl Olsen, Egle Kudirkiene, Kristiane Barington   +10 more
doaj   +1 more source

4.8 PLACENTAL NA/K-ATPASE INHIBITOR MARINOBUFAGENIN INDUCES ARTERIAL WALL FIBROSIS IN PREECLAMPSIA

Artery Research, 2018
Background: Previous studies implicated cardiotonic steroids, including Na/K-ATPase inhibitor marinobufagenin (MBG), in the pathogenesis of preeclampsia (PE). Immunoneutralization of heightened MBG by Digibind, a digoxin antibody, reduces blood pressure (
Olga Fedorova, Natalia Aglakova, Yulia Grigorova, Vitalily Reznik, Valintina Zernetkina, Wen Wei, Edward Lakatta, Alexei Bagrov   +7 more
doaj   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

The quality of stored umbilical cord and adult-donated whole blood in Mombasa, Kenya. [PDF]

, 2009
BACKGROUND: In sub-Saharan Africa umbilical cord blood may be a useful source of blood for transfusion. Before clinical trials, evidence is needed that cord blood donations, which vary greatly in volume, can be collected and stored into a fixed volume of
Hassall, O, Maitland, Kathryn, Robert Mwakesi, Douglas Denje, Hassall, Oliver, Thitiri, J, Mandaliya, K, Kathryn Maitland, Fegan, Gregory, Denje, Douglas, Bates, I, Bates, Imelda, Imelda Bates, Maitland, K, Oliver Hassall, Bates, Imelda; id_orcid, Wambua, Kongo, Pole, Lewa, Wambua, K, Mandaliya, Kishor, Mwakesi, Robert, Mwakesi, R, Lewa Pole, Fegan, G, Kongo Wambua, Kishor Mandaliya, Denje, D, Thitiri, Johnstone, Johnstone Thitiri, Pole, L, Gregory Fegan, Greg Fegan   +31 more
core   +1 more source

A comparative-analysis of glycosaminoglycans from human umbilical arteries in normal subjects and in pathological conditions affecting pregnancy

, 1992
BACKGROUND: Vascular cells express different phenotypes in adult and fetal vessels, and the extracellular matrix they synthesize should reflect these differences.
Cardoso, L. E. M., Erlich, R. B., Rudge, Marilza Vieira Cunha, Peraçoli, José Carlos, Mourao, P. A. S.   +4 more
core   +3 more sources

Umbilical venous catheter misplacement due to unexpected supernumerary patent umbilical artery

Maternal Health, Neonatology and Perinatology
Background Umbilical vein catheterization is relatively straightforward procedure because the vein is easily recognized as a single, large, thin-walled vessel.
Paola Papoff, Benedetto D’Agostino, Antonella Bitti, Valentina Pennetta, Valeria Avarino, Elena Caresta   +5 more
doaj   +1 more source