Results 171 to 180 of about 204,149 (306)

Umbilical cord haemangioma with pseudocyst detected in the first trimester of pregnancy. [PDF]

BMJ Case Rep
Jánošová S, Dudič R, Dankovčík R, Pšenková P.   +3 more
europepmc   +1 more source

MOCART 2.0 score of 60 or greater measured at 1 year post‐operatively predicts favourable clinical outcomes after surgical repair of tibiofemoral cartilage lesions

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose (1) To evaluate the relationship between the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) 2.0 score and post‐operative clinical outcomes following surgical repair of cartilage lesions in the tibiofemoral joint, and (2) to determine threshold values of the 1‐year MOCART 2.0 score associated with favourable patient ...
Hyun‐Soo Moon, Sungjun Kim, Chong‐Hyuk Choi, Min Jung, Kwangho Chung, Se‐Han Jung, Jin‐Gyu Kim, Min‐Cheol Park, Sung‐Hwan Kim   +8 more
wiley   +1 more source

Generation of Enucleated Erythrocytes From Lin−CD45−CD133+ Cells Isolated From Human Umbilical Cord Blood In Vitro

Stem Cells International
Ji He, Fang Wang, Qigang Zhan, Qi Sheng, Yanling Ying, Wei Zhang, Jinhui Liu, Faming Zhu   +7 more
doaj   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear, Billie Lianoglou, Ugur Hodoglugil, W. Patrick Devine, Ashutosh Lal, Juan Gonzalez, Teresa N. Sparks   +6 more
wiley   +1 more source

The correlation of umbilical cord blood quality and placental function with neonatal outcomes in fetal growth restriction. [PDF]

Front Med (Lausanne)
Zou L, Zeng Y, Zhao L, Shi C, Yang C, Zhu Y.   +5 more
europepmc   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Umbilical Cord Biomarkers of Nutritional and Metabolic Status in Neonates with Intrauterine Growth Restriction. [PDF]

J Clin Med
Toth IH, Pantea MM, Enatescu I, Filimon AT, Kali FY, Belei O.   +5 more
europepmc   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup, Steffen Thorsen, Morten Hanefeld Dziegiel, Olav Bjørn Petersen, Frederik Banch Clausen   +4 more
wiley   +1 more source