Results 191 to 200 of about 303,748 (255)

Fetal heart rate patterns associated with acidemia at fetal blood sampling during labor—An observational study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
The Swedish fetal heart rate (FHR) classification from 2017 identifies most FHR patterns associated with fetal acidemia as non‐normal, according to fetal blood sampling (FBS) in immediate connection to the ongoing FHR pattern. However, long‐standing FHR patterns with non‐repetitive decelerations of the types severe variable and late warrant increased ...
Erika Gyllencreutz   +4 more
wiley   +1 more source

Robotic surgery for paediatric neurogenic lower urinary tract dysfunction: a systematic review

open access: yesBJU International, Volume 135, Issue 4, Page 557-566, April 2025.
Objective To evaluate in a systematic review the outcomes, benefits, and limitations of robot‐assisted surgeries for paediatric neurogenic lower urinary tract dysfunction (LUTD), as robot‐assisted techniques have emerged as a potential alternative, offering enhanced precision, dexterity, and visualisation.
Ihtisham Ahmad   +6 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

CD93—An emerging vascular target in cancer therapy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira   +3 more
wiley   +1 more source

iPSC‐Derived iNK Progenitors Engraft and Generate NK Cells in Unconditioned and Autologous Immune Humanized Mice

open access: yesCell Proliferation, EarlyView.
Infusion of CXCR4‐expressing iNK progenitor (iNKP) cells derived from iPSCs can continuously generate iNK cells in an unconditioned and autologous PBMC humanised hIL15 mouse model. iNKP cell therapy has the potential to treat patients without the requirement for prior lymphodepletion. ABSTRACT NK cells exhibit inherently short persistence in vivo. Allo‐
Min Zhang   +14 more
wiley   +1 more source

Human Embryonic Stem Cell‐Derived Immunity‐And‐Matrix‐Regulatory Cells Attenuate Pulmonary Fibrosis via MMP1‐Mediated Collagen Degradation

open access: yesCell Proliferation, EarlyView.
Human embryonic stem cell‐derived Immunity‐and‐Matrix‐Regulatory Cells (IMRCs) effectively attenuate pulmonary fibrosis by secreting Matrix Metalloproteinase‐1 (MMP1), which directly degrades excess collagen I in the extracellular matrix. By directly degrading collagen I, IMRCs reverse ECM stiffness, suppress myofibroblast activation, and promote a ...
Zhongwen Li   +24 more
wiley   +1 more source

Predictive utility of a simple cranial magnetic resonance imaging score at term‐equivalent age for cerebral palsy

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This study evaluated the Total Abnormality Score (TAS) from cMRI at term‐equivalent age as a predictor of cerebral palsy (CP) in 137 infants born preterm or with low birthweight. Infants who developed CP had significantly higher TAS values (median 11 vs 2), with a TAS cut‐off of 9.5 demonstrating high sensitivity (88.9%) and specificity (91.4%) for CP ...
Anne‐Kathrin Dathe   +6 more
wiley   +1 more source

MRI, Child Opportunity Index, and 4‐year cognitive outcome after neonatal encephalopathy

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To evaluate the association of neonatal magnetic resonance imaging (MRI) and Child Opportunity Index (COI) with 4‐year cognitive outcomes after neonatal encephalopathy. Method This was a cross‐sectional analysis of 4‐year outcomes (interquartile range [IQR] = 48–52 months) in a single‐center prospective cohort of term neonatal ...
Ashley M. Bach   +7 more
wiley   +1 more source

Neuroimaging and neurophysiology in infantile‐onset epilepsy after neonatal stroke

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This population‐based retrospective cohort study of 55 newborn infants demonstrated that neonatal MRI and neonatal neurophysiology (amplitude‐integrated EEG, conventional EEG, and somatosensory evoked potentials) combined with follow‐up EEGs during the first year of life provide practical tools for identifying infants at the highest risk of developing ...
Sinikka La Grassa   +6 more
wiley   +1 more source

Short‐term welfare assessment of a single ultrasound‐guided adipose tissue aspiration in standing sedated horses

open access: yesEquine Veterinary Education, EarlyView.
Summary Background Adipose tissue‐derived mesenchymal stem cells (AT‐MSCs) are entering the market of orthobiologics suitable for managing musculoskeletal disorders in horses, due to their accessibility and reparative capacity. Ethical considerations in developing allogeneic products require a low‐morbidity approach to tissue harvest.
A. Nedergaard   +2 more
wiley   +1 more source

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