Results 201 to 210 of about 137,203 (257)
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Physiologically based pharmacokinetic (PBPK) modeling of placental drug transfer is an evolving tool for predicting fetal drug exposure. In this study, a pregnancy‐specific metformin PBPK model was developed, and the following four approaches were evaluated to predict metformin placental transfer: (1) perfusion‐limited model, and permeability ...
Jacqueline B. Tiley +5 more
wiley +1 more source
Biotechnical Multiscale Engineering of Scaffolds for Stem Cell and Organoid Research
Small, EarlyView.Biotechnical multiscale engineering consideration of geometric and structural parameters, which is called biotechnical multiscale engineering, has an influence on stem cell development and organogenesis comparable to that of molecular genetics and biochemical parameters.
Merle‐Johanna Küstner +13 more
wiley +1 more source
Small Science, EarlyView.The authors propose a novel use for the conventional hypoglycemic drug, dipeptidyl peptidase IV (DPP4+) inhibitor sitagliptin. Sitagliptin prevents scar formation during wound healing through fibroblast‐to‐adipocyte conversion at least by preventing DPP4‐mediated truncation of IGF‐1.
Ju‐Lei Zhang +14 more
wiley +1 more source
Immunomodulatory Biomaterials for Bone and Soft Tissue Chronic Inflammation Diseases
Small Science, EarlyView.This review analyzes immunomodulatory biomaterial strategies for treating chronic inflammatory disorders in bone and soft tissues. It explores emerging mechanisms for resolving inflammation while promoting tissue regeneration, offering insights for developing targeted immunotherapeutic approaches that bridge material science with immunology for ...
Yiming Li +7 more
wiley +1 more source
Hydrogel Microspheres for Biomedical Applications
Small Science, EarlyView.Hydrogel microspheres (HMs) play pivotal roles in biomedical applications, such as drug delivery, cell culture, regenerative medicine, wound healing, and tumor immunity. This review focuses on the latest findings to provide a more comprehensive understanding of HMs for biomedical applications.
Yingkang Huang +11 more
wiley +1 more source
Small Science, EarlyView.Infected diabetic foot ulcer endangers patients with high amputation, disability, mortality risks, and heavy medical burdens. This review analyzes its pathogenic factors, the limitations of current treatments, the breakthroughs of responsive antimicrobial biomaterials, and the challenge of multifunctional biomaterial innovations for further developing ...
Yaqi Yao +8 more
wiley +1 more source
Violence, Volition, and Volatility: The Embodied Subjectivity of Women in Cults
Symbolic Interaction, EarlyView.This paper explores the embodied experience of 25 women who are former cult members. By delving into the stories of three protagonists, we examine how these women engaged with and possibly redefined the cult's socially constructed notion of womanhood.
Shirly Bar‐Lev, Michal Morag
wiley +1 more source
Clinical significance of true umbilical cord knot: a propensity score matching study [PDF]
Ohad Houri +6 more
openalex +1 more source
Ultrasound in Obstetrics &Gynecology, EarlyView.ABSTRACT Objective Complete hydatidiform mole and coexisting normal fetus (CHMCF) is a rare condition for which there is significant heterogeneity in diagnosis, counseling and management of complications. The objective of this study was to summarize the prevalence of clinical outcomes in reported cases of CHMCF.
N. Salmeri +8 more
wiley +1 more source