Results 181 to 190 of about 11,214 (251)

Priming with interleukin‐1α and chemical hypoxia modulates the mesenchymal stem cell secretome to dampen microglial inflammation and promote neuroprotection

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose We hypothesised that dual priming of human bone marrow‐derived human mesenchymal stem cells (hBMSCs) with interleukin‐1alpha (IL‐1α) and CoCl2 (a hypoxia mimetic) would modulate their therapeutic efficacy for hypoxic‐ischaemic conditions. Experimental Approach hBMSCs were primed individually or in combination.
Maryam Adenike Salaudeen   +2 more
wiley   +1 more source

Clinical‐Grade Human Induced Pluripotent Stem Cell‐Derived Neural Precursor Cells Restore Motor Function and Preserve Striatal Integrity in a Quinolinic Acid‐Lesioned Rat Model of Huntington's Disease

open access: yesCell Proliferation, EarlyView.
Clinical‐grade HLA‐homozygous iPSC‐derived neural precursor cells restore motor function, rebuild striatal circuitry and reduce neuroinflammation in QA‐lesioned rats. These findings demonstrate robust neuronal replacement and microenvironment modulation, supporting their potential as a regenerative therapy for Huntington's disease.
Hyeonjoong Jeon   +6 more
wiley   +1 more source

Rare Secondary Neoplasms Arising in Epidermal Nevus: A Case Series and Literature Review

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Malignant transformation is known to occur with many nevi, such as nevus sebaceus. However, cases of secondary tumors developing in an epidermal nevus (EN) are rare, with only a few case reports documented in the literature. We present three unique cases of syringocystadenoma papilliferum (SCAP), syringofibroadenoma, trichilemmoma, and basal ...
Haya A. Homsi   +5 more
wiley   +1 more source

Characteristics of unilateral cerebral palsy according to gestational age at birth: A retrospective study

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Unilateral cerebral palsy (CP) affects 826 children in the Canadian CP Registry: 69% born at term, 15% 32 to 37 weeks, and 16% less than 32 weeks. Gestational age at birth did not affect impairments such as vision or hearing impairment, ambulation, seizures, or feeding difficulty.
Johanie Victoria Piché   +6 more
wiley   +1 more source

Regenerative potential of MSC-derived secretomes in radiation-induced xerostomia: Role of SDF-1, IL-10, and VEGF. [PDF]

open access: yesJ Oral Biol Craniofac Res
Mulyani SWM   +5 more
europepmc   +1 more source

Umbilical cord structure shapes feto-maternal heat exchange across mammals

open access: yes
Wan T   +8 more
europepmc   +1 more source

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