Results 21 to 30 of about 11,214 (251)

A Modified Protocol for the Isolation, Culture, and Characterization of Human Smooth Muscle Cells from the Umbilical Cord

Methods and Protocols, 2023
Background: Vascular smooth muscle cells (VSMCs) and vascular endothelial cells are key participants in the pathogenesis of atherosclerosis. Human umbilical vein endothelial cells (HUVECs) and VSMCs are useful models to design therapeutic strategies for ...
Asmaa Q. Ibrahim, Mohammed S. Abdullah, Mamoun Ahram, Shtaywy Abdalla   +3 more
doaj   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Histomorphological Analysis of Placental & Umbilical Cord Blood Vessels in Gestational Diabetes Mellitus [PDF]

Liaquat National Journal of Primary Care
Background: Gestational Diabetes Mellitus (GDM) is a primary health issue in our society. Diabetes during pregnancy presents various challenges that can impact the growth and development of the fetus, relying on the healthy functioning of the placenta ...
Anum Hafeez Dogar, Shagufta Nasreen, Samia Shahbaz, Amber Ilyas, Noor Ijaz, Sana Fatima Dogar   +5 more
doaj   +1 more source

Monochorionic Diamniotic Twins with Bordering Cord Insertions: Images and Outcome

Diagnostics, 2022
Twin pregnancy contributes to perinatal mortality, particularly monochorionic diamniotic twin pregnancy. Placental abnormalities are much more common in twin pregnancies than in singletons.
Lucian G. Pop, Madalina Piron, Viorica Radoi, Nicolae Bacalbasa, Oana D. Toader   +4 more
doaj   +1 more source

Association of Umbilical Coiling Index in Normal And Complicated Pregnanc

Diyala Journal of Medicine, 2019
Background: Umbilical cord index is the total number of coils divided by the total length of the umbilical cord in centimeters and an abnormal umbilical coiling index has been reported to be related to adverse fetal and pregnancy outcomes. Objective:
Snoor Jalal Mustafa , Abir Moheidin Said   +1 more
doaj   +2 more sources

The giant umbilical cord [PDF]

Archives of Disease in Childhood - Fetal and Neonatal Edition, 2005
The giant umbilical cord is a rare malformation of the umbilical cord that can easily be diagnosed on prenatal scans and is unmistakable postnatally. We report a case to highlight issues of this rare finding. Visual diagnosis is easy and surgical repair is usually required.
Wildhaber, Barbara, Antonelli, Eric, Pfister, Riccardo   +2 more
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Umbilical Cord Coiling Index and Perinatal Outcome [PDF]

Journal of Clinical and Diagnostic Research, 2013
Objectives: To evaluate the perinatal outcome with the abnormal umbilical cord coiling index. Study Design: This prospective study was carried out in the department of OBG at Adichunchangiri Institute of Medical Sciences, B.G.Nagara, Mandya ...
Nivedita S. Patil, Sunanda R. Kulkarni, Renu Lohitashwa   +2 more
doaj   +1 more source

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

Umbilical cord tissue cryopreservation: a short review

Stem Cell Research & Therapy, 2018
In this review we present current evidence on the possibility of umbilical cord tissue cryopreservation for subsequent clinical use. Protocols for obtaining umbilical cord-derived vessels, Wharton’s jelly-based grafts, multipotent stromal cells, and ...
Irina Arutyunyan, Timur Fatkhudinov, Gennady Sukhikh   +2 more
doaj   +1 more source