Results 41 to 50 of about 270,105 (271)

Phenotype of WJ-MSC obtained from human umbilical cords.

, 2018
Phenotype of WJ-MSC obtained from human umbilical cords.
Sonia Spalletta (5954390), Ivana Cacciatore (720571), Antonio Marino (5087378), Vincenzo Flati (3753451), Jacopo Di Gregorio (3753448), Gabriella D’Orazi (299722), Elena Toniato (5087366), Marco Marchisio (333289), Laura Pierdomenico (441750), Iole Robuffo (720577)   +9 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

From Fiber Bundles to Architected Membranes: Triply Periodic Minimal Surface Architectures for Biohybrid Artificial Lungs

Advanced Materials, EarlyView.
Additively manufactured triply periodic minimal surface (TPMS) membranes offer an architecture‐driven alternative to hollow fiber bundles in artificial lungs. Multiphysics simulations and endothelialized prototypes show that the 3D‐printable membrane architecture improves gas exchange, blood flow distribution, and hemocompatibility, enabling ...
Michael Pflaum, Kai P. Barbian, Florian Neuhaus, Gerrit Sitarz, Carolin Nölke, Sebastian V. Jansen, John Linkhorst, Lukas T. Hirschwald, Sebastian Brosch, Christian Certa, Ulrich Steinseifer, Matthias Wessling, Jutta Arens, Arjang Ruhparwar, Bettina Wiegmann   +14 more
wiley   +1 more source

Nuchal cords

, 2010
A loop of umbilical cord around the fetal neck (nuchal cord) is a common finding at delivery. Nuchal cords have been associated with an increased risk for adverse outcome [1-3].
Zimmermann, R, Schäffer, L
core   +2 more sources

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Umbilical Cord Coiling Index and Perinatal Outcome [PDF]

Journal of Clinical and Diagnostic Research, 2013
Objectives: To evaluate the perinatal outcome with the abnormal umbilical cord coiling index. Study Design: This prospective study was carried out in the department of OBG at Adichunchangiri Institute of Medical Sciences, B.G.Nagara, Mandya ...
Nivedita S. Patil, Sunanda R. Kulkarni, Renu Lohitashwa   +2 more
doaj   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

The quality of stored umbilical cord and adult-donated whole blood in Mombasa, Kenya. [PDF]

, 2009
BACKGROUND: In sub-Saharan Africa umbilical cord blood may be a useful source of blood for transfusion. Before clinical trials, evidence is needed that cord blood donations, which vary greatly in volume, can be collected and stored into a fixed volume of
Hassall, O, Maitland, Kathryn, Robert Mwakesi, Douglas Denje, Hassall, Oliver, Thitiri, J, Mandaliya, K, Kathryn Maitland, Fegan, Gregory, Denje, Douglas, Bates, I, Bates, Imelda, Imelda Bates, Maitland, K, Oliver Hassall, Bates, Imelda; id_orcid, Wambua, Kongo, Pole, Lewa, Wambua, K, Mandaliya, Kishor, Mwakesi, Robert, Mwakesi, R, Lewa Pole, Fegan, G, Kongo Wambua, Kishor Mandaliya, Denje, D, Thitiri, Johnstone, Johnstone Thitiri, Pole, L, Gregory Fegan, Greg Fegan   +31 more
core   +1 more source

Clinical significance of umbilical cord abnormalities: an observational study [PDF]

, 2022
Background: The well being of a foetus depends on the uncompromised placental function and normal blood flow through the umbilical vessels. If there are umbilical cord abnormalities, it can lead to perinatal complications.
Ravichandran, Monika R., Sundaravadivelu, Pavithra, Sowparnika, Alagu Sakthi, Karnal, C. Suhashini, Thangappah, Radha B. P.   +4 more
core   +1 more source