Results 61 to 70 of about 270,105 (271)

Histopathological morphology of placental umbilical cords and membranes among SHS and OHS-PWD EO-PE and LO-PE compared to NTN-P.

, 2022
Histopathological morphology of placental umbilical cords and membranes among SHS and OHS-PWD EO-PE and LO-PE compared to NTN-P.
Augustine Tawiah (12269826), Christian Obirikorang (577066), Agartha Odame Anto (12269823), Osei-Owusu Afriyie (12269817), Nicholas Akinwale Titiloye (11604108), Eric Adua (5523290), Youxin Wang (153032), Yaw Amo Wiafe (12006631), Max Efui Annani-Akollor (6551046), Enoch Odame Anto (7886804), WKBA Owiredu (12269820), Wei Wang (17594), David Antony Coall (12269814), Stephen Opoku (10499782), Emmanuel Akomanin Asiamah (7886810), Emmanuel Acheampong (3485225), Otchere Addai-Mensah (488140), Evans Asamoah Adu (7886813)   +17 more
core   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Gestação monoamniótica e entrelaçamento de cordão umbilical: relato de caso e revisão de literatura Monoamniotic pregnancy and umbilical cord entanglement: case report and literature review

Revista Brasileira de Ginecologia e Obstetrícia, 2010
As gestações gemelares monoamnióticas são muito raras, mas estão associadas a elevadas morbidade e mortalidade fetais. Há várias controvérsias em relação ao seguimento e conduta obstétrica diante do diagnóstico pré-natal de entrelaçamento de cordões ...
Marcelo Luís Nomura, Cleide Mara Mazotti Franzin, Helaine Milanez, Emílio Francisco Marussi, João Luis Carvalho Pinto Silva   +4 more
doaj   +1 more source

Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury

Advanced Science, EarlyView.
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang, Yaozhi He, Yanjiao Wang, Jingjing Zhang, Qishun Liang, Mengxian Jia, Yumin Wu, Zongjie Yuan, Ziwei Fan, Yuxuan Li, Huihui Zhang, Qinjiao Fu, Ying Wang, Zhihui Huang, Honglin Teng   +14 more
wiley   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

MANAGEMENT OF THE UMBILICAL CORD. [PDF]

JAMA: The Journal of the American Medical Association, 1902
The cutting of the cord is the first surgical operation to which most human beings are subjected and an operation to which all must submit. The management of the stump during its separation from the body and the care of the ulcer subsequently formed are surgical procedures upon which depend the health and perhaps the life of the infant. If the wound be
openaire   +2 more sources

Increased Endothelial Inflammation, sTie-2 and Arginase Activity in Umbilical Cords Obtained from Gestational Diabetic Mothers

PLoS ONE, 2013
Objective The aim of this study was to determine subclinical inflammation in umbilical vein derived endothelial cells (HUVECs) obtained from Asian Indian subjects with gestational diabetes (GDM) and to determine levels of angiogenic factors and arginase ...
Hemant Giri, S. Chandel, L. Dwarakanath, S. Sreekumar, M. Dixit   +4 more
semanticscholar   +1 more source

Self‐Amplified Activatable Fluorescent Probe for Early Diagnosis of Acute Kidney Injury and High‐Throughput Screening of Natural Protectants

Advanced Science, EarlyView.
The PS‐QRC nanoprobe employs L‐serine as a targeting ligand for kidney injury molecule‐1 (KIM‐1) to achieve accumulation in injured renal tissues. Upon activation by reactive oxygen species (ROS), it undergoes a self‐amplifying cascade to release fluorophores for near‐infrared fluorescence (NIRF) imaging, enabling ultra‐early diagnosis of acute kidney ...
Yahui Chen, Meihong Liu, Mengchao Ding, Ye Liu, Chuanxu Zhu, Mingye Gong, Zhixuan Huang, Yi Zhang, Wei Xue, Youyong Yuan, Kewei Wang   +10 more
wiley   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source