Results 101 to 110 of about 81,975 (261)
Advanced Science, EarlyView.A nano‐confined radical anion acts as a photothermal immunogenic amplifier. Kinetically stabilized nanoparticles couple high near‐infrared‐II (NIR‐II) photothermal efficacy with glutathione (GSH) depletion to boost reactive oxygen species (ROS) and immunogenic cell death (ICD).
Mengxin Mu +9 more
wiley +1 more source
Matrix Stiffness Induces Endothelial Network Senescence
Advanced Science, EarlyView.Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song +6 more
wiley +1 more source
Advanced Science, EarlyView.We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo +7 more
wiley +1 more source
CMC-surfaces, flat structures and umbilical points
, 2001 A short proof of the Caratheodory conjecture about index of an isolated umbilic on the convex 2-dimensional sphere is suggested. The argument is based on the study of geodesic lines near cone-type singularity of a metric induced by holomorphic quadratic differentials.
openaire +2 more sources
Advanced Science, EarlyView.ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning +7 more
wiley +1 more source
Advanced Science, EarlyView.A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang +12 more
wiley +1 more source
Liver Endothelia Orchestrate MASH‐Associated Macrophage Zonation Through FSTL1‐ITGA4 Axis
Advanced Science, EarlyView.Liver inflammation in MASH fundamentally hinges on the newly defined Kit/STAT2/FSTL1/ITGA4 axis. Declining endothelial Kit collapses normal hepatic zonation, driving an aberrant FSTL1 gradient that recruits pathogenic macrophages. Strikingly, targeting FSTL1‐ITGA4 with anti‐VLA4 restores spatial immune homeostasis and halts disease progression ...
Lin Sun +10 more
wiley +1 more source
Umbilical Hernias on Abdominal CT: A Retrospective Analysis of Prevalence and Reporting Patterns
Annals of Medicine and Medical SciencesIntroduction: Umbilical hernias (UMHs) are common abdominal wall defects in adults. They can cause serious complications such as strangulation and impingement.
Demet Doğan, M.D, Kağan Gökçe, M.D
doaj
Advanced Science, EarlyView.A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li +13 more
wiley +1 more source
On nondegenerate umbilical affine hypersurfaces in recurrent affine manifolds
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2004 Let $widetilde{M}$ be a differentiable manifold of dimension $geqslant 5$, which is endowed with a (torsion-free) affine connection $widetildeabla$ of recurrent curvature.
Zbigniew Olszak
doaj