Results 131 to 140 of about 10,643,617 (352)

Multidimensional replica-exchange method for free-energy calculations

, 2000
We have developed a new simulation algorithm for free-energy calculations. The method is a multidimensional extension of the replica-exchange method. While pairs of replicas with different temperatures are exchanged during the simulation in the original ...
Akio Kitao, Guo Z., Ikeguchi M., Kidera A., Ono S., Sugita Y., Sugita Y., Yuji Sugita, Yuko Okamoto   +8 more
core   +1 more source

Umbrella Review: Stress Levels, Sources of Stress, and Coping Mechanisms among Student Nurses

Nursing Reports
Prelicensure nursing students face significant stress from their education and clinical placements, highlighting the crucial need for the development of effective coping mechanisms with which to manage both academic and clinical responsibilities ...
L. Labrague
semanticscholar   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

An umbrella review on how digital health intervention co-design is conducted and described

npj Digital Medicine
Co-design has been suggested to improve intervention effectiveness and sustainability. However, digital health intervention co-design is inconsistently reported.
A. Kilfoy, T. Hsu, Charlotte Stockton-Powdrell, Pauline Whelan, Charlene H Chu, Lindsay Jibb   +5 more
semanticscholar   +1 more source

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola, Aleksandar Gigov, Hubertus G. M. Leufkens, Andrew Bate, Marie Louise De Bruin, Helga Gardarsdottir   +5 more
wiley   +1 more source

Dietary salt intake and cardiovascular outcomes: an umbrella review of meta-analyses and dose-response evidence

Annals of Medicine
Background Excessive salt intake is a known cardiovascular disease (CVD) risk factor, but the health impacts of both high and low sodium intake remain debated.
Fanjing Kong, Qian Liu, Qing Zhou, Pengyang Xiao, Yiling Bai, Tianyu Wu, Lina Xia   +6 more
doaj   +1 more source

The impact of gardening on well-being, mental health, and quality of life: an umbrella review and meta-analysis

Systematic Reviews
Background Gardening and horticultural therapy (HT) has been widely recognised as a multicomponent approach that has affected a broad range of health and well-being outcomes.
I. Panțiru, A. Ronaldson, N. Sima, A. Dregan, R. Sima   +4 more
semanticscholar   +1 more source

Understanding exam access arrangements in practice: Challenges and opportunities

British Educational Research Journal, EarlyView.
Abstract Secondary students with specific learning difficulties (SpLD) often face challenges with academic tasks, particularly with high‐stakes examinations. Exam access arrangements (EAA) are provided as reasonable adjustments to reduce disadvantage for students with SpLD.
Catherine Antalek, Amelia Roberts, Emma Sumner   +2 more
wiley   +1 more source

Evaluation of the Accuracy of Electronic Apex Locators in Modern Endodontics: An Umbrella Review

Medicina
Background and Objectives: To achieve success in endodontic treatment, it is essential to properly perform the steps of shaping, cleansing and obturation.
Massimo Pisano, Giuseppe Sangiovanni, Eugenio Frucci, Michela Scorziello, Giuseppina De Benedetto, Alfredo Iandolo   +5 more
doaj   +1 more source

Missed Nursing Care; Prioritizing the Patient’s Needs: An Umbrella Review

Healthcare
The objective of this review of reviews was to identify the reasons for missed nursing care and to shed light on how nurses prioritize what care they miss.
Iokasti Papathanasiou, Vasileios Tzenetidis, K. Tsaras, S. Zyga, M. Malliarou   +4 more
semanticscholar   +1 more source