Results 41 to 50 of about 74,323 (305)
, 2001 Software developers spend most of their time modifying and maintaining existing products. This is because systems, and consequently their design, are in perpetual evolution before they die. Nevertheless, dealing with this evolution is a complex task. Before evolving a system, structural modi cations are often required.
Sunyé, Gerson +3 more
openaire +2 more sources
ISPRS International Journal of Geo-Information, 2020 Scientific reproducibility is essential for the advancement of science. It allows the results of previous studies to be reproduced, validates their conclusions and develops new contributions based on previous research.
Benito M. Zaragozí +2 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Sistem Informasi Penjualan Pada TB Harmonis Menggunakan Metode FAST
Jurnal Sisfokom, 2020 The development of computerized technology requires many parties to compete in using a computerized system to improve the performance and effectiveness of a company or agency.
R.M. Nasrul Halim
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
ModellingUnmanned surface vehicles (USVs) have great application prospects in defense, environmental surveillance and offshore energy due to their cost-effectiveness and long-duration mission ability.
Yifei Peng +3 more
doaj +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Implementasi Ekonomi Melingkar pada Sistem Informasi Pengelolaan Hutan Mangrove
JEPIN (Jurnal Edukasi dan Penelitian Informatika), 2019 Penelitian ini bertujuan membangun sebuah sistem berbasis komputer yang dapat membantu pengelolaan hutan mangrove dengan menadopsi konsep ekonomi melingkar (Circular Economy).
Eva Faja Ripanti
doaj +1 more source
Perancangan Aplikasi Penjualan Berbasis Web pada CV. Jawi
Jurnal Informatika dan Rekayasa Perangkat Lunak, 2020 Penyajian informasi tentang penjualan produk di tempat kerja praktek yaitu CV.JAWI yang menggunakan cara manual yaitu promosi produk dengan menggunakan media brosur dan tanya langsung pada pihak perusahaan, sehingga informasi tentang penjualan produk ...
Bayu Trisakti, Fandy Indra Pratama
doaj +1 more source