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Systems Modeling Language (SysML) is a Unified Modeling Language (UML) profile intended for application in systems engineering. This text is inspired by lack of literature on SysML in Serbian language.
Miloš D. Jevtić +2 more
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Model Validation in Ontology Based Transformations [PDF]
Model Driven Engineering (MDE) is an emerging approach of software engineering. MDE emphasizes the construction of models from which the implementation should be derived by applying model transformations. The Ontology Definition Meta-model (ODM) has been
Jesús M. Almendros-Jiménez +1 more
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Cognitive Behaviors Modeling Using UML Profile: Design and Experience
To achieve model reuse in combat effectiveness simulation systems development, cognitive decision behaviors are usually implemented using a scripting language, which is separate from the programming language used to implement simulation models. Therefore,
Zhi Zhu +3 more
doaj +1 more source
Applying Model-Driven Engineering to Distributed Ledger Deployment
Distributed Ledger Technology (DLT) enables data storage in a decentralized manner among collaborating parties. The software architecture of such solutions encompasses models placed in the relevant architectural views.
Tomasz Gorski, Jakub Bednarski
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Pengembangan Aplikasi Manajemen Rekrutmen Karyawan Menggunakan Metode Profile Matching
Human Resources (HR) is one of the important aspects in the company, because it will manage many aspects such as technology, resources, and capital, therefore the process of hiring and allocating training is important in the company.
Hery Hery +3 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
UML-profile for multimedia software architectures [PDF]
Multimedia technology is increasingly being used to create reliable and effective communication environments. However, the design of multimedia applications is currently driven more by intuition than by empirically or theoretically derived design guidelines.
Derdour Makhlouf +4 more
openaire +1 more source

