Results 81 to 90 of about 1,121,600 (292)

Effect of temperature dependency on constrained orthotropic unbounded body with a cylindrical cavity due to pulse heat flux

open access: yesJournal of Thermal Science and Technology, 2015
In this paper, the thermoelastic interactions in an orthotropic unbounded body containing a cylindrical cavity are studied. This problem is solved by using the Green and Naghdi's (GN) generalized thermoelasticity model.
Ashraf M. ZENKOUR, Ahmed E. ABOUELREGAL
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha   +4 more
wiley   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

open access: yesAdvanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo   +18 more
wiley   +1 more source

Dirichlet problems for semilinear elliptic equations with a fast growth coefficient on unbounded domains

open access: yesElectronic Journal of Differential Equations, 2005
When an unbounded domain is inside a slab, existence of a positive solution is proved for the Dirichlet problem of a class of semilinear elliptic equations that are similar either to the singular Emden-Fowler equation or a sublinear elliptic equation ...
Zhiren Jin
doaj  

Existence of the solution to a nonlocal-in-time evolutional problem

open access: yesNonlinear Analysis, 2014
This work is devoted to the study of a nonlocal-in-time evolutional problem for the first order differential equation in Banach space. Our primary approach, although stems from the convenient technique based on the reduction of a nonlocal problem to its ...
Volodymyr Makarov   +2 more
doaj   +1 more source

The regularized trace of a self adjoint differential operator of higher order with unbounded operator coefficient

open access: yes, 2011
Let L0 and L be operators which are formed by the differential expressions in the space H1 = L2(0,p; >H), with same boundary conditions, where H is an infinite dimensional separable Hilbert space.Here, A is an unbounded self adjoint operator in H and,
Yonca Sezer   +3 more
core   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

Elliptic Operators with Unbounded Coefficients

open access: yes, 2017
Aim of this manuscript is to give generation results and some Hardy inequalities concerning elliptic operators with unbounded coefficients of the form Au = div(aDu) + F ·Du + V u where V is a real valued function, a(x) = (akl(x)) is symmetric and satisfies the ellipticity condition and a and F grow to infinity.
openaire   +2 more sources

A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers

open access: yesAdvanced Science, EarlyView.
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels   +2 more
wiley   +1 more source

Cores for parabolic operators with unbounded coefficients

open access: yesJournal of Differential Equations, 2009
The authors consider the following nonautonomous parabolic Cauchy problem: \[ \begin{cases} D_{s}u(s,x)=(\mathcal{A}u)(s,x), &s>r,\;x\in \mathbb R^N\\ u(r,x)=f(x), &x\in \mathbb R^{N} \end{cases} \quad (r\in \mathbb R) \] where \[ (\mathcal{A}u)(s,x)=\sum_{i,j=1}^{N}q_{ij}(s,x)D_{ij}u(s,x)+\sum_{i=1}^{N}b_{i}(s,x)D_{i}u(s,x),\quad s\in \mathbb R,\;x\in
LORENZI, Luca Francesco Giuseppe   +1 more
openaire   +3 more sources

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