Results 51 to 60 of about 154,676 (283)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Existence results for a coupled system of nonlinear fractional differential equations with boundary value problems on an unbounded domain

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2013
This paper deals with the existence results for solutions of coupled system of nonlinear fractional differential equations with boundary value problems on an unbounded domain. Also, we give an illustrative example in order to indicate the validity of our
Neda Khodabakhshi, S. Mansour Vaezpour
doaj   +1 more source

Numerical Solitons of Generalized Korteweg-de Vries Equations

open access: yes, 2005
We propose a numerical method for finding solitary wave solutions of generalized Korteweg-de Vries equations by solving the nonlinear eigenvalue problem on an unbounded domain. The artificial boundary conditions are obtained to make the domain finite. We
Camassa   +7 more
core   +2 more sources

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Exponential decay for the damped wave equation in unbounded domains

open access: yes, 2015
We study the decay of the semigroup generated by the damped wave equation in an unbounded domain. We first prove under the natural geometric control condition the exponential decay of the semigroup.
Alinhac S.   +12 more
core   +2 more sources

Unbounded Hölder Domains

open access: yesThe Journal of Geometric Analysis
Abstract Motivated by the classical bounded Hölder domains, we introduce the notion of an unbounded simply connected Hölder domain. We prove analytic and geometric characterizations of these domains with the aid of the spherical metric and the hyperbolic metric.
openaire   +1 more source

Defining functions for unbounded $C^m$ domains

open access: yesRevista Matemática Iberoamericana, 2013
For a domain \Omega\subset\mathbb{R}^n , we introduce the concept of a uniformly C^m defining function. We characterize uniformly C^m defining functions in terms of the signed ...
Harrington, Phillip, Raich, Andrew
openaire   +4 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Nonlinear p-Laplacian Problems on Unbounded Domains [PDF]

open access: yesProceedings of the American Mathematical Society, 1992
We consider the p p -Laplacian problem \[ − d i v ( a ( x ) | ∇ u | p − 2 ∇ u ) + b
openaire   +2 more sources

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