Results 41 to 50 of about 64,214 (233)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Differentially private posterior summaries for linear regression coefficients
The Journal of Privacy and Confidentiality, 2018 In Bayesian regression modeling, often analysts summarize inferences using posterior probabilities and quantiles, such as the posterior probability that a coefficient exceeds zero or the posterior median of that coefficient.
Gilad Amitai, Jerome Reiter
doaj +1 more source
On the relation of three theorems of analysis to the axiom of choice
, 2017 In what follows, essentially two things will be accomplished: Firstly, it will be proven that a version of the Arzel\`a--Ascoli theorem and the Fr\'echet--Kolmogorov theorem are equivalent to the axiom of countable choice for subsets of real numbers ...
Fellhauer, Adrian
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Functional boundedness of balleans
, 2019 We pose some open problems related to boundedness of real-valued functions on balleans and coarse spaces. Also we prove that the Bergman property of groups is a coarse invariant.
Banakh, Taras, Protasov, Igor
core +1 more source
Arthritis Care &Research, EarlyView.Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr +5 more
wiley +1 more source
Maximum principles for boundary-degenerate second-order linear elliptic differential operators
, 2013 We prove weak and strong maximum principles, including a Hopf lemma, for smooth subsolutions to equations defined by linear, second-order, partial differential operators whose principal symbols vanish along a portion of the domain boundary.
Feehan, Paul M. N.
core +1 more source
Advanced Materials, EarlyView.This work introduces an injectable mesoporous silica rod scaffold that confines lentiviral vectors to the injection site, enabling localized dendritic cell recruitment and transduction. The platform sustains antigen expression, promotes robust T‐cell activation, and enhances antitumor immunity.
Thanh Loc Nguyen +12 more
wiley +1 more source
Random fixed point theorems for a random operator on an unbounded subset of a Banach space
Applied Mathematics Letters, 2008 The authors obtain random fixed point theorems for nonexpansive random operators and claim to improve certain results of \textit{G.\,Isac} and \textit{S.\,Z.\thinspace Németh} [J.~Math.\ Anal.\ Appl.\ 314, No.\,2, 500--512 (2006; Zbl 1090.47041)] and \textit{J.--P.\thinspace Penot} [Proc.\ Am.\ Math.\ Soc.\ 131, No.\,8, 2371--2377 (2003; Zbl 1035.47043)
Beg, Ismat, Abbas, Mujahid
openaire +1 more source