Results 71 to 80 of about 1,121,216 (274)

An Effective and Practical Probabilistic Simplified Neutrosophic Approach for Accurate and Reliable Innovative Design Evaluation for Digital Media Arts [PDF]

Neutrosophic Sets and Systems
The evaluation and classification of digital artworks remain a challenging task due to the inherent uncertainty, subjectivity, and imprecision in artistic design.
Yang Zhang, Yuzhuo Zhang
doaj   +1 more source

Enhance the Uncertainty Modeling Ability of Fuzzy Grey Cognitive Maps by General Grey Number

IEEE Access, 2020
In real-life systems, people cannot get precise data. The data are represented in the forms of interval or multiple intervals in many cases. Most intelligent algorithms are designed for precise data in algorithm research.
Jun Chen, Xudong Gao, Jia Rong
doaj   +1 more source

A framework for modeling uncertainty in regional climate change [PDF]

, 2015
In this study, we present a new modeling framework and a large ensemble of climate projections to investigate the uncertainty in regional climate change over the United States (US) associated with four dimensions of uncertainty.
Gao, X, Monier, E, Schlosser, CA, Scott, JR, Sokolov, AP   +4 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Recursive Thick Modeling and the Choice of Monetary Policy in Mexico [PDF]

By following the spirit in Favero and Milani (2005), we use recursive thick modeling to take into account model uncertainty for the choice of optimal monetary policy.
Arnulfo Rodriguez, Pedro N. Rodriguez
core   +3 more sources

Implementing Loss Distribution Approach for Operational Risk

, 2009
To quantify the operational risk capital charge under the current regulatory framework for banking supervision, referred to as Basel II, many banks adopt the Loss Distribution Approach.
Artzner, Aue, Basel Committee on Banking Supervision, Bedard, Berger, Böcker, Böcker, Böcker, Böcker, Bühlmann, Bühlmann, Chavez-Demoulin, Chernobai, Chernobai, Cont, Cruz, Dalla Valle, Degen, Efron, Embrechts, Embrechts, Embrechts, Embrechts, Embrechts, Ergashev, Frachot, Gerhold, Giacometti, Gilks, Gustafsson, Hess, Joe, Johnson, King, Klugman, Lambrigger, Lehmann, Lindskog, Luo, Luo, Marshall, McNeil, Mignola, Mignola, Nelson, Nešlehová, Panjer, Peters, Peters, Peters, Peters, Powojowski, Press, Robert, Sandström, Schaller, Shevchenko, Shevchenko, Shevchenko, Sundt, Wüthrich   +60 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source