Results 91 to 100 of about 3,213,103 (353)

Strain tracking with uncertainty quantification

, 2023
AbstractThe ability to detect and quantify microbiota over time has a plethora of clinical, basic science, and public health applications. One of the primary means of tracking microbiota is through sequencing technologies. When the microorganism of interest is well characterized or knowna priori, targeted sequencing is often used. In many applications,
Younhun Kim, Colin J. Worby, Sawal Acharya, Lucas R. van Dijk, Daniel Alfonsetti, Zackary Gromko, Philippe Azimzadeh, Karen Dodson, Georg Gerber, Scott Hultgren, Ashlee M. Earl, Bonnie Berger, Travis E. Gibson   +12 more
openaire   +2 more sources

CLOSURE LAW MODEL UNCERTAINTY QUANTIFICATION

International Journal for Uncertainty Quantification, 2022
The prediction uncertainty in simulators for industrial processes is due to uncertainties in the input variables and uncertainties in specification of the models, in particular the closure laws. In this work, the uncertainty in each closure law was modeled as a random variable and the parameters of its distribution were optimized to correctly quantify ...
Strand, Andreas, Kjølaas, Jørn, Bergstrøm, Trond Harald, Steinsland, Ingelin, Hellevik, Leif Rune   +4 more
openaire   +2 more sources

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Dakota A Multilevel Parallel Object-Oriented Framework for Design Optimization Parameter Estimation Uncertainty Quantification and Sensitivity Analysis: Version 6.14 Theory Manual.

, 2020
The Dakota (Design Analysis Kit for Optimization and Terascale Applications) toolkit provides a flexible and extensible interface between simulation codes and iterative analysis methods.
Brian M. Adams, Mohamed S. Ebeida, M. Eldred, J. Jakeman, L. Swiler, John Stephens, Dena M. Vigil, Timothy M. Wildey, W. Bohnhoff, John P. Eddy, Kenneth T. Hu, K. Dalbey, Lara Bauman, P. Hough   +13 more
semanticscholar   +1 more source

The Parallel C++ Statistical Library for Bayesian Inference: QUESO

, 2015
The Parallel C++ Statistical Library for the Quantification of Uncertainty for Estimation, Simulation and Optimization, Queso, is a collection of statistical algorithms and programming constructs supporting research into the quantification of uncertainty
Malaya, Nicholas, McDougall, Damon, Moser, Robert D.   +2 more
core   +1 more source

Uncertainty Quantification For Learned ISTA

2023 IEEE 33rd International Workshop on Machine Learning for Signal Processing (MLSP), 2023
to appear at the 33rd IEEE International Workshop on Machine Learning for Signal Processing (MLSP 2023)
Hoppe, Frederik, Verdun, Claudio Mayrink, Krahmer, Felix, Laus, Hannah, Rauhut, Holger   +4 more
openaire   +2 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Probabilistic analysis of concrete beams during fire [PDF]

, 2011
In this paper a simple computational tool is presented, which provides insight in the time and temperature dependent reliability of concrete beams during fire.
Annerel, Emmanuel, Caspeele, Robby, Taerwe, Luc, Van Coile, Ruben   +3 more
core  

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source