Results 41 to 50 of about 181,335 (383)

Caffeine reverses the unconsciousness produced by light anesthesia in the continued presence of isoflurane in rats

PLoS ONE, 2020
Currently no drugs are employed clinically to reverse the unconsciousness induced by general anesthetics. Our previous studies showed that caffeine, when given near the end of an anesthesia session, accelerated emergence from isoflurane anesthesia ...
A. Fox, Kyle R Wagner, V. Towle, Kelvin G Xie, Zheng Xie   +4 more
semanticscholar   +1 more source

Disruption of thalamic functional connectivity is a neural correlate of dexmedetomidine-induced unconsciousness [PDF]

, 2014
Understanding the neural basis of consciousness is fundamental to neuroscience research. Disruptions in cortico-cortical connectivity have been suggested as a primary mechanism of unconsciousness.
Akeju, Oluwaseun, Arabasz, Grae, Brown, Emery N, Catana, Ciprian, Chonde, Daniel B, Contreras Ramirez, Violeta, Habeeb, Kathleen, Hooker, Jacob M, Hsu, Shirley, Izquierdo-Garcia, David, Loggia, Marco L, Napadow, Vitaly, Pavone, Kara J, Purdon, Patrick L, Rhee, James, Vazquez, Rafael   +15 more
core   +3 more sources

Connectivity differences between consciousness and unconsciousness in non-rapid eye movement sleep: a TMS–EEG study

Scientific Reports, 2019
The neuronal connectivity patterns that differentiate consciousness from unconsciousness remain unclear. Previous studies have demonstrated that effective connectivity, as assessed by transcranial magnetic stimulation combined with electroencephalography
Minji Lee, Benjamin Baird, O. Gosseries, Jaakko O. Nieminen, M. Boly, B. Postle, G. Tononi, Seong-Whan Lee   +7 more
semanticscholar   +1 more source

Dynamics of recovery from anaesthesia-induced unconsciousness across primate neocortex.

Brain : a journal of neurology, 2020
How the brain recovers from general anaesthesia is poorly understood. Neurocognitive problems during anaesthesia recovery are associated with an increase in morbidity and mortality in patients.
Shaun R. Patel, J. Ballesteros, Omar J. Ahmed, Pamela Huang, Jessica B. Briscoe, E. Eskandar, Y. Ishizawa   +6 more
semanticscholar   +1 more source

Changes in Whole Brain Dynamics and Connectivity Patterns during Sevoflurane- and Propofol-induced Unconsciousness Identified by Functional Magnetic Resonance Imaging

Anesthesiology, 2019
What We Already Know about This Topic The extent to which alterations within specific brain networks impairs communication among networks remains unknown What This Article Tells Us That Is New In a volunteer functional magnetic resonance study, general ...
D. Golkowski, S. Larroque, A. Vanhaudenhuyse, A. Plenevaux, M. Boly, C. Di Perri, A. Ranft, G. Schneider, Steven Laureys, D. Jordan, V. Bonhomme, R. Ilg   +11 more
semanticscholar   +1 more source

A conscious choice: Is it ethical to aim for unconsciousness at the end of life?

Bioethics, 2020
One of the most commonly referenced ethical principles when it comes to the management of dying patients is the doctrine of double effect (DDE). The DDE affirms that it is acceptable to cause side effects (e.g. respiratory depression) as a consequence of
A. Takla, J. Savulescu, D. Wilkinson
semanticscholar   +1 more source

Unconscious mental imagery [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2020
Historically, mental imagery has been defined as an experiential state—as something necessarily conscious. But most behavioural or neuroimaging experiments on mental imagery—including the most famous ones—do not actually take the conscious experience of the subject into consideration.
openaire   +3 more sources

Quantitative assessment of the relationship between behavioral and autonomic dynamics during propofol-induced unconsciousness

bioRxiv, 2020
During general anesthesia, both behavioral and autonomic changes are caused by the administration of anesthetics such as propofol. Propofol produces unconsciousness by creating highly structured oscillations in brain circuits.
S. Subramanian, P. Purdon, R. Barbieri, E. Brown   +3 more
semanticscholar   +1 more source

Microtubule-Stabilizer Epothilone B Delays Anesthetic-Induced Unconsciousness in Rats

eNeuro
Visual Abstract Volatile anesthetics are currently believed to cause unconsciousness by acting on one or more molecular targets including neural ion channels, receptors, mitochondria, synaptic proteins, and cytoskeletal proteins.
Sana Khan, Yixiang Huang, D. Timuçin, Shantelle Bailey, Sophia Lee, Jessica Lopes, Emeline Gaunce, Jasmine Mosberger, M. Zhan, Bothina Abdelrahman, Xiran Zeng, Michael C. Wiest   +11 more
semanticscholar   +1 more source

Sample entropy analysis for the estimating depth of anaesthesia through human EEG signal at different levels of unconsciousness during surgeries

PeerJ, 2018
Estimating the depth of anaesthesia (DoA) in operations has always been a challenging issue due to the underlying complexity of the brain mechanisms. Electroencephalogram (EEG) signals are undoubtedly the most widely used signals for measuring DoA.
QUAN LIU, Li Ma, S. Fan, M. Abbod, J. Shieh   +4 more
semanticscholar   +1 more source