Results 151 to 160 of about 22,546 (283)

Compromised DNA replication in gut cells underlies sensitivity to genotoxic stress in the tardigrade Hypsibius exemplaris

The FEBS Journal, EarlyView.
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas, Pauline Fontanié, Benjamin Lacroix, Maria Dolores Molina, María Moriel‐Carretero   +4 more
wiley   +1 more source

Revisiting T cells: Innate actions and emerging links to innate memory response. [PDF]

J Immunol
Tran KA, Divangahi M.
europepmc   +1 more source

3D printing in core facilities – Low pain, high gain

Journal of Microscopy, EarlyView.
Abstract Three‐dimensional (3D) printing has rapidly developed from a niche hobbyist activity into a widely accessible and indispensable technology across multiple scientific disciplines. Within microscopy, optical engineering laboratories and imaging core facilities, 3D printing enables creating customised solutions for sample holders, optical ...
Mohammad Goudarzi, Maximilian Schuster, Arthur Milberger, Manuel Gunkel, Stefan Terjung, Gabriel Krens   +5 more
wiley   +1 more source

A new mode of action for unconventional NMDA receptors. [PDF]

Elife
Smith I.
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Shigella Effector VirA Suppresses Plant Immunity by Compromising PRA1.F3‐Dependent Accumulation of FLS2 at the Plasma Membrane

Plant, Cell &Environment, EarlyView.
ABSTRACT Surface immune receptors such as flagellin‐sensitive 2 (FLS2) are critical for plant defence, and their accumulation at the plasma membrane is tightly controlled by the endomembrane system. Here, we identify the Arabidopsis thaliana prenylated Rab acceptor PRA1.F3 as a positive regulator required for efficient accumulation of FLS2 at the ...
Sung Hee Jo, Sukyoung Jung, Myoung Hui Lee, Inhwan Hwang, Jeong Mee Park   +4 more
wiley   +1 more source

A grapeful discovery: Reservoir computing with wine beads. [PDF]

PNAS Nexus
Fortulan R, Raeisi Kheirabadi N, Chiolerio A, Adamatzky A.   +3 more
europepmc   +1 more source

Do They Want, Can They, and Have They Been Asked? Generational Differences in Reasons for Non‐Voting in Switzerland

Swiss Political Science Review, EarlyView.
Abstract In many advanced democracies, newer generations and younger citizens are less likely to vote than earlier generations and older individuals. However, despite this being an established empirical matter, less is known about the reasons why they decide to stay away from the polls. This’ Age‐Period‐Cohort’ (APC) study analyzes generational and age
Reto Mitteregger, Thomas Jocker
wiley   +1 more source

Nutritional Plasticity, Waste Bioconversion, and Insect Detoxification in the Anthropocene. [PDF]

Insects
Christ-Ribeiro A, Zacheski JBA, da Silva Lucas AJ, Kupski L.   +3 more
europepmc   +1 more source

The what, which, when, why and who of Off responses in the auditory system

The Journal of Physiology, EarlyView.
Abstract figure legend In this article, we will first review ‘What’ different mechanisms are involved in the generation of Off responses at the sub‐cortical and cortical level of the auditory system. Then, we evaluate ‘Which’ stimulus properties elicit Off responses at the different levels of the auditory system.
Jean‐Marc Edeline, Robert C. Liu
wiley   +1 more source