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Nutrition Research in Aging Dogs and Cats: What We Know and What We Need to Do. [PDF]
Cai X, Mao H, Zhu L.
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Undenatured type II collagen and its role in improving osteoarthritis
Ageing Research Reviews, 2023Osteoarthritis (OA) is a degenerative joint disease, affecting 32.5 million US adults or 242 million people worldwide. There is no cure for OA. Many animal and clinical trials showed that oral administration of undenatured type II collagen could significantly reduce the incidence of OA or alleviate the symptoms of articular cartilage.
Mouming Zhao, Jianping Wu, Lin Zheng
exaly +3 more sources
Safety and toxicological evaluation of undenatured type II collagen
Toxicology Mechanisms and Methods, 2010Previous research has shown that undenatured type II collagen is effective in the treatment of arthritis. The present study evaluated the broad-spectrum safety of UC-II by a variety of toxicological assays including acute oral, acute dermal, primary dermal irritation, and primary eye irritation toxicity.
Debasis Bagchi +2 more
exaly +3 more sources
Water-Soluble Undenatured Type II Collagen Ameliorates Collagen-Induced Arthritis in Mice
Journal of Medicinal Food, 2013Earlier studies have reported the efficacy of type II collagen (C II) in treating rheumatoid arthritis (RA). However, a few studies have investigated the ability of the antigenic collagen to induce oral tolerance, which is defined as active nonresponse to an orally administered antigen.
Manashi Bagchi +2 more
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Points of undenatured type II collagen application in musculoskeletal pain syndromes treatment
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2022The dominant collagen of the cartilaginous matrix in adults is type II collagen. The amount of type II collagen in the intercellular matrix of cartilage is significantly reduced against the background of musculoskeletal system diseases. The basis of articular cartilage is hyaline cartilage tissue consisting of chondrocytes with tissue-specific antigens
O.A. Shavlovskaya +2 more
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Undenatured type II collagen in the treatment of osteoarthritis
Orvosi hetilap, 2021Összefoglaló. Az arthrosis az ízületeket alkotó porc, csont és a környező lágy részek leépülésével járó betegség. A betegség jelentős fájdalommal jár, progresszív, az ízület strukturális átalakulását és ennek következtében jelentős funkcióvesztést és életminőség-romlást okoz.
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An Overview of a Novel, Water-Soluble Undenatured Type II Collagen (NEXT-II)
Journal of the American College of Nutrition, 2015Osteoarthritis, the most common form of arthritis, is a crippling, chronic debilitating bone disease that commonly affects humans, dogs, and horses. Inflammation and inflammatory responses are key factors for causing swelling, redness, pain, and loss of movement in arthritic animals and humans.We developed a novel, water-soluble, undenatured type II ...
Orie, Yoshinari +2 more
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Food Chemistry, 2023
This study aimed to investigate the effects of dynamic high-pressure homogenization (DHPH), dynamic high-pressure microfluidization (DHPM), and wet media milling (WMM) processes on the particle size, microstructure, triple helix structure, wettability and suspension stability of insoluble undenatured type II collagen (IUC-II).
Jinfang Liu, Like Mao
exaly +3 more sources
This study aimed to investigate the effects of dynamic high-pressure homogenization (DHPH), dynamic high-pressure microfluidization (DHPM), and wet media milling (WMM) processes on the particle size, microstructure, triple helix structure, wettability and suspension stability of insoluble undenatured type II collagen (IUC-II).
Jinfang Liu, Like Mao
exaly +3 more sources
Journal of Veterinary Pharmacology and Therapeutics, 2005
In large breed dogs, arthritis is very common because of obesity, injury, aging, immune disorder, or genetic predispositions. This study was therefore undertaken to evaluate clinical efficacy and safety of undenatured type‐II collagen (UC‐II) in obese‐arthritic dogs. Fifteen dogs in three groups received either no UC‐II (Group I) or UC‐II with 1 mg/day
L A, Deparle +6 more
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In large breed dogs, arthritis is very common because of obesity, injury, aging, immune disorder, or genetic predispositions. This study was therefore undertaken to evaluate clinical efficacy and safety of undenatured type‐II collagen (UC‐II) in obese‐arthritic dogs. Fifteen dogs in three groups received either no UC‐II (Group I) or UC‐II with 1 mg/day
L A, Deparle +6 more
openaire +2 more sources

