Results 131 to 140 of about 3,467,566 (283)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Vulnerability and Resilience Determinants of under-five mortality changes in Zambia [PDF]
Trends in under-five mortality were favorable in Zambia in the twelve years following independence (1964-1975), as a result of favorable political and economic context and generous health, education and social policies, largely financed by the exports of
Eneas GAKUSI, Michel GARENNE
core
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Factors contributing to under-5 child mortality in Nigeria: A narrative review
MedicineDespite repeated efforts by the Nigerian government and the international community, under-5 child mortality remains alarmingly high in Nigeria. This narrative review aims to reassess the key factors contributing to this persistent public health challenge.
David B. Olawade +6 more
openaire +2 more sources
Infant and Under-five mortality in Sub-Suharan Africa
, 2019 Describe the causes of infant and under-five mortality in Sub-Saharan African region with attention to Angola, and providing possible solutions. Also, the list of factors that influence child mortality are mentioned.gjnépegészségügyinappaliangolBSc ...
Israel, Frederico Epalanga Albano
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
, 2011 This study investigates the extent of bias in the estimates of infant and under-five mortality derived from the Brass children ever born children surviving (CEB/CS) method as a result of HIV/AIDS.
Mutemaringa, Themba
core
, 2022 Magister Philosophiae - MPhilMortality is one of the significant vital events for which a government collects data, especially child mortality, because it is one of the contributing indicators that are used to assess the wellbeing of a nation. Globally,
Hera, Robynn Ashley
core