Results 81 to 90 of about 2,756,571 (326)

Assessment of Under-5 Mortality Rates in İstanbul Using the Geographic Information System [PDF]

open access: yesErciyes Tıp Dergisi/Erciyes Medical Journal, 2016
WOS ...
Babaoğlu, Ülken Tunga   +2 more
openaire   +3 more sources

Protein kinase FAM20C—when subcellular localization matters

open access: yesFEBS Letters, EarlyView.
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley   +1 more source

Lung cancer epidemiology in North Sardinia, Italy [PDF]

open access: yes, 2013
Background The aim of this study was to analyze and describe the epidemiological characteristics and trends of lung cancer in North Sardinia, Italy, in the period 1992–2010.
Attene, Federico   +7 more
core   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

IJCM_374A: Parental perspectives on the MR vaccination campaign in Mangaluru insights from government mandates: A cross-sectional study

open access: yesIndian Journal of Community Medicine
Background: Measles is the leading cause of child mortality in India. MR vaccine provides immunity against measles & rubella and was offered in 2 doses – 9 completed months and 16-24 months of age.
Rekha T   +9 more
doaj   +1 more source

An update on explaining the rural-urban gap in under-five mortality in India

open access: yesBMC Public Health, 2022
Background Rural Indians have higher mortality rates than urban Indians. However, the rural-urban gap in under-five mortality has changed is less researched.
Chandan Kumar, Piyasa, Nandita Saikia
doaj   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

IJCM_149A: Profile of injuries among children admitted to a tertiary care hospital of Mangalore city, South India.

open access: yesIndian Journal of Community Medicine
Background: Childhood injuries represent a significant public health concern worldwide, with a considerable impact on morbidity and mortality rates among children.
Rathaur Siddharth   +9 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

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