The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Impact of HIV on estimates of child mortality derived using the summary birth history (CEB/CS) Method [PDF]
This study investigates the extent of bias in the estimates of infant and under-five mortality derived from the Brass children ever born children surviving (CEB/CS) method as a result of HIV/AIDS.
Mutemaringa, Themba
core +1 more source
Impact of Human Development Index on Mortality Rates in Iran
Background and Objectives: Human Development Index (HDI) is an important indicator of a country’s development. On the other hand, mortality indicators are the most important indicators of the health of a society.
AM Mosadeghrad +3 more
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Mapping neonatal and under-5 mortality in India [PDF]
Praveen, Kumar, Nalini, Singhal
openaire +2 more sources
Under-5 mortality rates with 95% confidence intervals (CI) in 27 sub-Saharan African countries.
Under-5 mortality rates with 95% confidence intervals (CI) in 27 sub-Saharan African countries.
Andre M. N. Renzaho (3219330) +2 more
core +1 more source
Income groups results (dep. Vars: Infant mortality/under-5 mortality).
Income groups results (dep. Vars: Infant mortality/under-5 mortality).
Aminat Olayinka Olohunlana (13804452) +4 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

