Results 141 to 150 of about 7,042,235 (309)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

An Analysis of Pricing Strategy and Price Dispersion on the Internet [PDF]

open access: yes
Using prices obtained from shopbots, we test several hypotheses regarding the economics of information and optimal search. We find that price dispersion is positively (negatively) related to product price and the number of sellers in cross-sectional ...
Richard Cohen   +2 more
core  

Inverse scattering designs of dispersion-engineered single-mode planar waveguides

open access: yes
We use an inverse-scattering (IS) approach to design single-mode waveguides with controlled linear and higher-order dispersion. The technique is based on a numerical solution to the Gelfand-Levitan-Marchenko integral equation, for the inversion of ...
Poletti, F., May, A.R., Zervas, M.N.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Persistent Price Dispersion in Online Markets [PDF]

open access: yes
Using data from one of the Internet’s leading price comparison sites for consumer electronics products, we present evidence for the persistence of price dispersion for 36 homogeneous products. The markets for these products are “thick” with an average of
Michael R. Baye   +2 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

PRICE DISPERSION, SEARCH COSTS AND CONSUMERS AND SELLERS HETEROGENEITY IN RETAIL FOOD MARKETS [PDF]

open access: yes
Price dispersion, i.e. a homogeneous product sold at different prices by different sellers, is among the most replicated findings in empirical economics.
Rosanna Nisticò, Giovanni Anania
core  

Quantifying numerical dispersion in non-orthogonal FDTD meshes

open access: yes, 2002
Numerical electromagnetic models such as FDTD are widely used for the design and analysis of structures, including antennas. Numerical dispersion is one of the main sources of error that degrade the accuracy of the results-for each structure of interest,
Nilavalan, R, Railton, CJ, Craddock, IJ
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

COM-Poisson Clustering of Correlated Bivariate Over- and Under-Dispersed Counts

open access: yes, 2016
Ruan (2015) recently proposed using a finite mixture model with components modelled by Gaussian copula with Poisson margins (BP-GCD) as the basis for model-based clustering of bivariate correlated counts. Although the Poisson distribution is a useful model for modelling count data, the distribution is constrained by its equi-dispersion assumption ...
openaire   +2 more sources

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