Results 121 to 130 of about 7,042,235 (309)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A note on exponential dispersion models which are invariant under length-biased sampling
Length-biased sampling situations may occur in clinical trials, reliability, queueing models, survival analysis and population studies where a proper sampling frame is absent.In such situations items are sampled at rate proportional to their length so ...
Bar-Lev, S.K. +1 more
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Gap solitons in moiré optical lattice with quartic dispersion
Scientific ReportsThis work investigates the theoretical properties and stability mechanisms of semi-infinite gap solitons in moiré optical lattices governed by quartic dispersion.
Keyan Liu +6 more
doaj +1 more source
Equi-Under-Dispersed Possion Distribution (EUPoisson)
Abstract In this study, we propose an Equi-Under-dispersed Poisson distribution derived from a finite mixture of weighted Poisson distributions. This probability distribution is a simple, parsimonious, and flexible option suitable for modeling under-dispersed count data.
openaire +1 more source
Bell Test Correlations Under Dispersion and Sphere Hardening
Draft paper abstract: Bell test experiments exhibit correlation functions proportional to cos(∆θ) or cos2(∆θ), traditionally interpreted as evidence for non-locality or the failure of local realism. In this paper, we show that such correlations arise naturally and locally within Actualation Theory (AT) due to state dispersion, which invokes high ...
openaire +2 more sources
Inflation and Wage Dispersion [PDF]
A large body of empirical work has demonstrated that higher inflation, especially when it is unexpected, leads to greater dispersion in the distribution of price changes across subaggregates.
Allan Drazen, Daniel S. Hamermesh
core
, 2009 The objective of this paper is to provide an investigation, using large eddy simulations, into the dispersion of aircraft jets in co-flowing take-off conditions.
S.S. Aloysius +3 more
core +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source