Results 101 to 110 of about 10,362,785 (303)

Theoretical Re-evaluations of Scaling Relations between SMBHs and Their Host Galaxies–2. Importance of AGN Feedback Suggested by Stellar Age–Velocity Dispersion Relation

Frontiers in Astronomy and Space Sciences, 2017
We present the galactic stellar age—velocity dispersion relation obtained from a semi-analytic model of galaxy formation. We divide galaxies into two populations: galaxies which have over-massive/under-massive black holes (BHs) against the best-fitting ...
Hikari Shirakata, Toshihiro Kawaguchi, Takashi Okamoto, Tomoaki Ishiyama   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

The dispersion of terahertz signals propagating in a hypersonic plasma sheath under a time-varying magnetic field [PDF]

AIP Advances
This paper investigates the dispersion relation of terahertz waves propagating in a hypersonic plasma sheath under a low-frequency, time-varying magnetic field.
YiMing Zou, Junyi Zhang, Kai Yuan, Ziyang Zhao   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Who Searches for Low Prices? Population Characteristics and Price Dispersion in the Market for Prescription Drugs [PDF]

We examine the relationship between population characteristics and price dispersion for 75 prescription drugs in five markets. Based on models of price dispersion, we consider that search costs are likely lower for the elderly, who are repeat purchasers.
Adrienne M. Ohler
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Study on Liquid Hydrogen Leakage Dispersion Behavior and Synergistic Mitigation by Barrier Walls and Air Curtains in a Hydrogen Production and Refueling Station

Fire
Compared with gaseous hydrogen at ambient temperature, liquid hydrogen (LH2) possesses a higher volumetric energy density and is therefore regarded as one of the most economically viable hydrogen storage and transportation options. However, the extremely
Xingyu Liu, Bo Yuan, Shiyan Zeng, Linzhi Xu, Chunyan Song, Nianfeng Xu, Tianqi Yang, Yonghua Cai, Jinsheng Xiao   +8 more
doaj   +1 more source

Interrelation of the concept of “uncertainty” in the information theory and theory of measurements

MATEC Web of Conferences, 2017
The problem of determining the optimal number of multiple measurements based on the type of the error distribution density of the measuring means is considered. The laws of distribution of a random variable are obtained, they ensure the extreme values of
Kopp Vadim, Balakin Alexey, Balakina Natalya, Preys Vladimir   +3 more
doaj   +1 more source

Equi-Under-Dispersed Possion Distribution (EUPoisson)

Abstract In this study, we propose an Equi-Under-dispersed Poisson distribution derived from a finite mixture of weighted Poisson distributions. This probability distribution is a simple, parsimonious, and flexible option suitable for modeling under-dispersed count data.
openaire   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source