Results 241 to 250 of about 10,362,785 (303)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Short-Term Stable Catchment-Level Metabolic Structure in Urban Wastewater Revealed by Untargeted Metabolomics. [PDF]

Metabolites
Li D, Wang Y, Shi Y, Ma Z, Fang Y, Ma Y, Wang B, Duan H, Lv K.   +8 more
europepmc   +1 more source

pH-Dependent Changes in the Structural and Functional Properties of Quinoa Protein Isolates in Aqueous Dispersions. [PDF]

Foods
Astorga-Oquendo L, Harte FM, Campanella OH.   +2 more
europepmc   +1 more source

Silver Nanoparticles Suppress Apple Fire Blight: Antibacterial Activity, Reduced Carbohydrate-Containing EPS Content, and Altered Host Antioxidant Responses. [PDF]

Plants (Basel)
Khina AG, Mukhina MT, Gordeev AS, Biktasheva LR, Mikhaylov DM, Lisichkin GV, Krutyakov YA.   +6 more
europepmc   +1 more source

Direct observations of submesoscale turbulence driving mesoscale eddy leakage. [PDF]

Sci Adv
Cao H, Jing Z, Fox-Kemper B, Qiu B, Lacasce JH, Yan T.   +5 more
europepmc   +1 more source

Solid Dispersion Characteristics of an Oscillatory Microfluidic Mixer: An Experimental and Numerical Investigation. [PDF]

Micromachines (Basel)
Lu Y, Sun H, Qin Y.
europepmc   +1 more source