Results 71 to 80 of about 1,552,146 (293)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Maternal Death in Indonesia: Follow-up Study of the 2010 Indonesia Population Census [PDF]

, 2016
Background: Among ASEAN countries, Indonesia is the country with high maternal mortality ratio (MMR) and unable to reach target of reduction of MMR. In order to reduce the MMR target, the government of Indonesia needs evidence to evaluate and design the ...
Afifah, T. (Tin), Pangaribuan, L. (Lamria), Rizkianti, A. (Anissa), Saptarini, I. (Ika), Senewe, F. P. (Felly), Tejayanti, T. (Teti), Usman, Y. (Yuslely)   +6 more
core   +2 more sources

ASSESSMENT OF THE QUALITY OF ACCOUNTING OF DEATHS OF PATIENTS WITH MALIGNANT NEOPLASMS IN RUSSIA

Исследования и практика в медицине, 2016
It is presented the comparative assessment of the quality of the records of patients who died from malignant neoplasms (MN), according to the report of Rosstat used to calculate mortality rates (form No.
G. V. Petrova, V. V. Starinskiy, O. P. Gretsova   +2 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Baboon-to-human liver transplantation [PDF]

, 1993
Our ability to control both the cellular and humoral components of xenograft rejection in laboratory experiments, together with an organ shortage that has placed limits on clinical transplantation services, prompted us to undertake a liver ...
A Tzakis, A Zeevi, A Zeevi, A.J Demetris, A.J Demetris, Alper, Asonuma, Bailey, Barnard, Cano, Crawford, Essex, Francavilla, H Doyle, Hasan, Hitchcock, I.R Marino, Iwaki, J Fung, Jacobson, Karpas, Kelly, M Michaels, M Trucco, M Trucco, Moran, Porter, S Kusne, S Kusne, S Todo, Starzl, Starzl, Starzl, Starzl, Starzl, T.E Starzl, Takaya, Todo, Tzakis, V Warty, V Warty, W.A Rudert, W.A Rudert, Wolpl   +43 more
core   +1 more source

Confiabilidade da declaração de causa básica de mortes infantis em região metropolitana do sudeste do Brasil Reliability of the medical certificates of underlying cause of infant deaths in a metropolitan region of southeastern Brazil

Revista de Saúde Pública, 1994
A partir de dados coletados para um estudo sobre a mortalidade infantil na região metropolitana de Belo Horizonte, MG, Brasil, foi selecionada uma amostra aleatória de óbitos infantis ocorridos em 1989, para avaliar a concordância da causa básica de ...
Elisabeth F. Mendonça, Eugênio M.A. Goulart, José A.D. Machado   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Using Verbal Autopsy to Measure Causes of Death: the Comparative Performance of Existing Methods. [PDF]

, 2014
Monitoring progress with disease and injury reduction in many populations will require widespread use of verbal autopsy (VA). Multiple methods have been developed for assigning cause of death from a VA but their application is restricted by uncertainty ...
A Khosravi, Aarti Kumar, Abdullah H Baqui, Abraham D Flaxman, AD Flaxman, AD Flaxman, AD Lopez, AD Ngo, Alan D Lopez, Alireza Vahdatpour, Andrea Stewart, Arup Dutta, B Hernández, B Kodio, Bernardo Hernández, Bruce Neal, C Engmann, C Rao, CD Mathers, Charles Atkinson, Christopher JL Murray, CJ Murray, CJ Murray, CJ Murray, CJ Murray, D Campos, D Chandramohan, David Phillips, Devarsetty Praveen, DG Bassani, Diozele Sanvictores, Dolores Ramírez-Villalobos, Emily Dantzer, F Baiden, G Yang, G Yang, Gary L Darmstadt, Hazel Remolador, Henry D Kalter, HR Chowdhury, Ian Riley, IM Gaskin, Instituto Nacional de Estatística, J Pattaraarchachai, KJ Foreman, Lalit Dandona, LT Ruzicka, Marilla Lucero, MC Asuzu, Michael K Freeman, Minerva Romero, Mwanaidi Said, N Dhingra, P Byass, P Jha, P Mahapatra, Peter Serina, PW Setel, R Development Core Team, R Joshi, R Kumar, R Lozano, R Lozano, Rafael Lozano, RM Bell, Robert Black, Rohina Joshi, Said Mohammed Ali, Sara Gómez, Saurabh Mehta, SK Morris, SL James, Spencer L James, Summer Lockett Ohno, Sunil Sazawal, TN Krishnamurti, United Nations, Usha Dhingra, V Gajalakshmi, V Gajalakshmi, Veronica Tallo, Vinita Das, Vishwajeet Kumar, W Polprasert, Wafaie Fawzi, Zul Premji   +85 more
core   +7 more sources

Diabetes-related deaths in Australia, 2001–2003 [PDF]

Highlights This report presents information on diabetes-related deaths in Australia between 2001 and 2003 using death certificate data. The term ‘diabetes-related deaths’ is used in this analysis to refer to deaths where diabetes was considered to have ...

core  

Causas múltiples de muerte

Revista Cubana de Higiene y Epidemiología, 1998
Se presenta un estudio de causas múltiples de muerte, en la población cubana de 1 año y más de edad. La información se obtuvo de una muestra de 2 036 defunciones ocurridas durante 4 meses consecutivos en 22 municipios del país.
Norma Eneida Ríos Massabot, Ana Consuelo Mesa Machado, Arnaldo Tejeiro Fernández   +2 more
doaj