Results 61 to 70 of about 4,354,150 (246)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Applying the Liouville–Lanczos method of time-dependent density-functional theory to warm dense matter

Matter and Radiation at Extremes
Ab initio modeling of dynamic structure factors (DSF) and related density response properties in the warm dense matter (WDM) regime is a challenging computational task.
Zhandos A. Moldabekov, Sebastian Schwalbe, Thomas Gawne, Thomas R. Preston, Jan Vorberger, Tobias Dornheim   +5 more
doaj   +1 more source

Divide-and-Conquer Dual-Architecture Convolutional Neural Network for Classification of Hyperspectral Images

Remote Sensing, 2019
Convolutional neural network (CNN) is well-known for its powerful capability on image classification. In hyperspectral images (HSIs), fixed-size spatial window is generally used as the input of CNN for pixel-wise classification.
Jie Feng, Lin Wang, Haipeng Yu, Licheng Jiao, Xiangrong Zhang   +4 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Decomposition-Based Multiobjective Evolutionary Algorithm for Community Detection in Dynamic Social Networks

The Scientific World Journal, 2014
Community structure is one of the most important properties in social networks. In dynamic networks, there are two conflicting criteria that need to be considered.
Jingjing Ma, Jie Liu, Wenping Ma, Maoguo Gong, Licheng Jiao   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A multi-task genetic programming approach for online multi-objective container placement in heterogeneous cluster

Complex & Intelligent Systems
Owing to the potential for fast deployment, containerization technology has been widely used in web applications based on microservice architecture.
Ruochen Liu, Haoyuan Lv, Ping Yang, Rongfang Wang   +3 more
doaj   +1 more source

Restricted Boltzmann Machine-Based Approaches for Link Prediction in Dynamic Networks

IEEE Access, 2018
Link prediction in dynamic networks aims to predict edges according to historical linkage status. It is inherently difficult because of the linear/non-linear transformation of underlying structures.
Taisong Li, Bing Wang, Yasong Jiang, Yan Zhang, Yonghong Yan   +4 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A multitasking ant system for multi-depot pick-up and delivery location routing problem with time window

Complex & Intelligent Systems
Instant delivery service has brought great convenience to our modern life. In order to improve its efficiency, multi-depot pick-up-and-delivery location routing problem with time windows (MDPDLRPTW) is proposed in this paper.
Haoyuan Lv, Ruochen Liu, Jianxia Li
doaj   +1 more source