Results 81 to 90 of about 8,566,469 (316)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Understanding Statistics

open access: yes, 1987
x;ill.;326hal ...
Chalmer,Bruce J.
core  

Multiple Hierarchical Cross-Scale Transformer for Remote Sensing Scene Classification

open access: yesRemote Sensing
The Transformer model can capture global contextual information but does not have an inherent inductive bias. In contrast, convolutional neural networks (CNNs) are highly praised in computer vision due to their strong inductive bias and local spatial ...
Dan Zhang   +5 more
doaj   +1 more source

Divide-and-Conquer Dual-Architecture Convolutional Neural Network for Classification of Hyperspectral Images

open access: yesRemote Sensing, 2019
Convolutional neural network (CNN) is well-known for its powerful capability on image classification. In hyperspectral images (HSIs), fixed-size spatial window is generally used as the input of CNN for pixel-wise classification.
Jie Feng   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Fostering Mathematical Conceptual Understanding through ChatGPT-Assisted Discovery Learning

open access: yes
This study examines the impact of the Discovery Learning model assisted by ChatGPT on students’ mathematical conceptual understanding. Employing a quasi-experimental Non-Equivalent (Pretest–Posttest) Control Group design, two classes participated: one ...
Utami, Dian Nur, Sugiman, Sugiman
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Understanding Utterances an Introduction to Pragmatics

open access: yes, 1992
viii, 191 hlm, 24 ...
Diane -Blakemore
core  

A multi-task genetic programming approach for online multi-objective container placement in heterogeneous cluster

open access: yesComplex & Intelligent Systems
Owing to the potential for fast deployment, containerization technology has been widely used in web applications based on microservice architecture.
Ruochen Liu   +3 more
doaj   +1 more source

Decomposition-Based Multiobjective Evolutionary Algorithm for Community Detection in Dynamic Social Networks

open access: yesThe Scientific World Journal, 2014
Community structure is one of the most important properties in social networks. In dynamic networks, there are two conflicting criteria that need to be considered.
Jingjing Ma   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy