Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
An anganwadi center provides essential services to extremely vulnerable and underprivileged communities, ensuring that these services are accessible at the beneficiaries' doorsteps to promote their active participation.
Subal Das, Manisha Ghritlahre
doaj
Impact of underweight on patients with non-metastatic cancers receiving curative anticancer therapy; analysis of large oncology database in Saudi Arabia [PDF]
Emad Tashkandi
openalex +1 more source
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Prevalence of underweight in the Roma population from a rural area in the south part of Romania- Călăraşi county [PDF]
Emilia Rusu +7 more
openalex +1 more source
Underweight and overweight/obesity among adults in Afghanistan: Prevalence and correlates from a national survey in 2018 [PDF]
Supa Pengpid, Karl Peltzer
openalex +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
Impact of gestational weight gain on perineal injury and obstetric anal sphincter injury among underweight primiparous women [PDF]
Itamar Gilboa +6 more
openalex +1 more source
Impact of being underweight on the long-term outcomes of patients with gastric cancer [PDF]
Kazuhiro Migita +8 more
openalex +1 more source

