Results 161 to 170 of about 213,377 (343)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Assessment of Stunting, Underweight and Wasting Among ICDS Children Aged 24 to 60 Months in Chhattisgarh, India

open access: yesOnline Journal of Health & Allied Sciences
An anganwadi center provides essential services to extremely vulnerable and underprivileged communities, ensuring that these services are accessible at the beneficiaries' doorsteps to promote their active participation.
Subal Das, Manisha Ghritlahre
doaj  

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Prevalence of underweight in the Roma population from a rural area in the south part of Romania- Călăraşi county [PDF]

open access: bronze, 2020
Emilia Rusu   +7 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Impact of gestational weight gain on perineal injury and obstetric anal sphincter injury among underweight primiparous women [PDF]

open access: hybrid
Itamar Gilboa   +6 more
openalex   +1 more source

Impact of being underweight on the long-term outcomes of patients with gastric cancer [PDF]

open access: bronze, 2015
Kazuhiro Migita   +8 more
openalex   +1 more source

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