Results 121 to 130 of about 5,842,410 (204)

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Perceptions and Acceptability of <i>Artemisia annua</i> Herbal Tea for Malaria Treatment: A Qualitative Study in Kalima Health Zone, Maniema, Democratic Republic of the Congo. [PDF]

Healthcare (Basel)
Munyangi Wa Nkola J, Zalagile PA, Lukuke Mbutshu H, Kabala Munyemo S, Bin Eradi IR, Camara A.   +5 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Annotated checklist of the butterflies (Lepidoptera: Papilionoidea) of Burkina Faso, West Africa-synthesis and new occurrences. [PDF]

J Insect Sci
Jamonneau T, Ringim AS, Libert M, Reyes Camargo AC, Coache A, Bouyer J.   +5 more
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Soil fertility controls on tropical forest productivity and mortality: synthesis and roadmap. [PDF]

New Phytol
Wong MY, Batterman SA, Lucas JM, Fleischer K, Ashton MS, Bauters M, Burslem DFRP, Cushman KC, Dalling JW, Doetterl S, Esquivel-Muelbert A, Fortunel C, Holm JA, Huanca-Nunez N, Liang G, Libalah MB, Lira-Martins D, Medina-Vega JA, Muller-Landau HC, Needham J, Ordway EM, Sánchez-Juliá M, Toro L, Xu X, Wright SJ, Zuquim G, Gora EM.   +26 more
europepmc   +1 more source

Moroccan subaltern voices narrated: the historical imaginary of race and the legacy of slavery in Rabbaj's Le Lutteur [The Wrestler] and El Hachimi's Dhākirat al-narjis [The Daffodil's Memory]. [PDF]

Soc Identities, 2022
Goikolea-Amiano I, Simour L.
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Monitoring the Prevalence and Distribution of Chytrid Fungus (<i>Batrachochytrium dendrobatidis</i>) in the Kihansi Spray Toad (<i>Nectophrynoides asperginis</i>) Population in the Kihansi Gorge Spray Wetlands, Tanzania. [PDF]

Ecol Evol
Mtui DT, Haule LJ, Ogutu JO, Preston A, Braun J, Newmark WD, Kohi EM, Kimera J, Mtalika M, Adam H, Mtoka S, Shayo F, Keyyu JD, Makange MR, Hakizimana JN, Misinzo G, Mjingo EE.   +16 more
europepmc   +1 more source

A high coverage reference transcriptome assembly of pea (Pisum sativum L.) mycorrhizal roots. [PDF]

Vavilovskii Zhurnal Genet Selektsii, 2020
Afonin AM, Leppyanen IV, Kulaeva OA, Shtark OY, Tikhonovich IA, Dolgikh EA, Zhukov VA.   +6 more
europepmc   +1 more source