Results 41 to 50 of about 170,574 (301)
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
CBR Withdrawals: Understanding the Uneven Occurrence Across the Caribbean
, 2018 Multiple studies have highlighted the Caribbean as one of the geographic regions most severely impacted by the decline in correspondent banking relationships (CBRs).
Inter-American Development Bank
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
The “law” of uneven and combined development: Part 1 [PDF]
, 2018 Since the 1990s there has been an upsurge of academic interest in Trotsky’s concept of uneven and combined development, but relatively little attention has been paid to its intellectual antecedents. This first of two articles will reconstruct the sources
Davidson, Neil, Neil Davidson
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Development and regional characteristics of the Hungarian information and communication sector (ICT)
Netcom, 2009 The rapid development of IC technologies and in parallel the increasing demand for more information and knowledge from the actors of economy, institutions and members of society created the ICT-sector into the core of “new economy” and information ...
Gábor Nagy, Imre Kanalas
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
CENTRALISATION OR PERIPHERLISATION? A ‘NEW DEAL” IN URBAN-RURAL RELATIONS [PDF]
Studia Universitatis Babeş-Bolyai: Geographia, 2015 Centralisation or Peripheralization? A ‘New Deal’ in Urban-Rural Relations. Beginning with the new century a new concept of regional planning has established itself in Europe, being strongly related to long-term development, especially in post-industrial
IBOLYA TÖRÖK
doaj +4 more sources
Transnational Political Economy and the Development of Tourism: A Critical Approach
Social Sciences, 2019 Following a Marxist and, more specifically, a global capitalism perspective, this paper outlines the peculiar characteristics of tourism to argue that the recent developments of this sector have prominently contributed to the transnational integration ...
George Liodakis
doaj +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source