Results 91 to 100 of about 4,536 (249)

Analysis of Frame Structure under Uneven Settlement and Earthquake [PDF]

open access: yesProceedings of the 2015 International Conference on Advanced Engineering Materials and Technology, 2015
Huiling Wang, Fei Qin, Peng Deng
openaire   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

open access: yesAdvanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li   +7 more
wiley   +1 more source

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen   +18 more
wiley   +1 more source

CALCULATION METHOD OF RESPONSE OF CLUSTERED PIPELINES SUBJECTED TO UNEVEN GROUND SETTLEMENTS

open access: yesDoboku Gakkai Ronbunshu, 1997
近年, 電力ケーブル保護管として多条多段配管が使用されつつあるが, 多条多段配管に関する不等沈下計算法は未だ確立されていない. 1995年01月17日に発生した兵庫県南部地震ではライフライン施設も例外なく甚大な被害を受けた. 地震時不等沈下も含めてライフライン施設の耐震評価手法を早急に整備するのは重要な課題である.本研究では, 以上のことを踏まえて, いままで不等沈下設計計算法が確立できていなかった多条多段配管を研究対象として, 実験値を説明できるモデルの設定と上・下段管の応答の相違を明らかにすることおよび継手の設計を目的として, 多条多段配管の不等沈下設計計算法を提案するとともに, 継手特性と地盤ばね係数の設定および取付部の条件などが管路の応答に与える影響を検討する.
Shiro Takada, Tengyan Li, Jyunji Higashi
openaire   +2 more sources

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

open access: yesAdvanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan   +24 more
wiley   +1 more source

Transferable Deep Reinforcement Learning With Edge‐Contour‐Depth Fusion for Autonomous Wireless Capsule Endoscopy Navigation

open access: yesAdvanced Science, EarlyView.
This study presents an anatomical landmark‐guided DRL framework for autonomous wireless capsule endoscopy navigation. Using a lightweight edge‐contour‐depth fusion module, it achieves over 97% coverage across diverse gastric anatomies. To ensure reliability, a two‐stage sim‐to‐real pipeline with an adaptive dynamic programming controller mitigates ...
Haoxuan Wu   +16 more
wiley   +1 more source

Assessment of metro running safety and comfort under uneven tunnel settlement

open access: yesJournal of Physics: Conference Series
Abstract Uneven tunnel settlement has adverse effects of varying degrees on tunnel structures, track structures, and metro train operating conditions. With increasing emphasis on the safety and comfort of metro operations, it is necessary to assess the metro running safety and comfort under uneven settlement conditions.
Xianfeng Zhang, Long Wang, Jinfeng Zhang
openaire   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

open access: yesAdvanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang   +9 more
wiley   +1 more source

Cotton Recruits Soil‐Derived Delftia tsuruhatensis to Suppress Aphid Detoxification Via Salicylic Acid‐Mediated Defense

open access: yesAdvanced Science, EarlyView.
This study systematically reveals a complex interactive network involving plants, microbes, and insects, elucidating the ecological and molecular mechanisms by which cotton enhances its resistance to aphids through the active recruitment of the beneficial soil bacterium Delftia tsuruhatensis.
Hui Xue   +11 more
wiley   +1 more source

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

open access: yesAdvanced Science, EarlyView.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin   +12 more
wiley   +1 more source

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