Results 81 to 90 of about 7,670 (198)

Decreased Toll-like Receptor (TLR) 2 and 4 Expression in Spermatozoa in Couples with Unexplained Recurrent Spontaneous Abortion (URSA)

Iranian Journal of Allergy, Asthma and Immunology, 2019
Studies have shown that toll-like receptors (TLRs) play some important roles in reproductive processes such as ovulation, spermatogenesis, sperm capacitation, fertilization, and pregnancy to the best of our knowledge, no study has evaluated the ...
Nasrin Sereshki, Alireza Andalib, Ataollah Ghahiri, Ferdos Mehrabian, Roya Sherkat, Abbas Rezaei   +5 more
doaj   +1 more source

Effects of progestogens in women with preterm premature rupture of membranes [PDF]

, 2019
Different strategies have been adopted for prevention of spontaneous preterm birth, including use of progestogens. So far, five randomized trials have been published evaluating the efficacy of progestogens in women with PPROM, including a total of 425 ...
DI SARNO, ROSSANA, Raffone, Antonio, Saccone, Gabriele   +2 more
core   +1 more source

Innate Immunity and Microbial Recognition in Reproduction: From Barrier Defense to Maternal–Fetal Tolerance

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Graphical abstract illustrating the barrier defense–tolerance framework of reproductive innate immunity. Across the female and male reproductive tracts and the maternal–fetal interface, epithelial barriers, innate sensors, immune cells, and microbial signals are integrated to preserve reproductive homeostasis.
Xianlin Rao, Li Zou, Yao Yao, Changling Liu   +3 more
wiley   +1 more source

Genetic Factors in Pregnancy Loss [PDF]

, 2013
Pregnancy loss is the most common obstetric complication. Multiple factors have been associated with recurrent or sporadic pregnancy loss, and genetic factors, particularly at earlier gestational ages, are the most important ones.
Francisco, C, Lima, A, Martins, L, Mendes, N, Serrano, F   +4 more
core  

Slow Fetal Heart Rate before Miscarriage in the Early First Trimester Predicts Fetal Aneuploidy in Women with Recurrent Pregnancy Loss [PDF]

, 2018
Establishing whether miscarriages result from fetal aneuploidy or other factors is important for treating recurrent pregnancy loss. We examined the relationship between fetal heart rate (FHR) before miscarriage in the early first trimester and fetal ...
Hasegawa, Toru, Hiramatsu, Yuji, Kamada, Yasuhiko, Kotani, Sayoko, Kubo, Kotaro, Nakatsuka, Mikiya, Sakamoto, Ai   +6 more
core   +1 more source

Variants in AKR1D1 and Infant Mortality: Should Bile Acid Screening be a Routine Part of Newborn Screening?

American Journal of Medical Genetics Part A, Volume 200, Issue 4, Page 971-977, April 2026.
ABSTRACT Biallelic pathogenic variants in AKR1D1 cause Δ4‐3‐oxosteroid 5β‐reductase deficiency, disrupt bile acid synthesis, and result in Congenital Bile Acid Synthesis defect type 2 (CBAS2). CBAS2 presents in infancy with cholestasis, coagulopathy, and failure to thrive.
Jade Hudson, Stephanie Hyunh, Bojana Rakic, Cornelius Boerkoel   +3 more
wiley   +1 more source

A Retrospective Analysis of Pregnancy Outcomes Following Frozen Embryo Transfer in Patients With Persistent Chronic Endometritis: A Five‐Year Single‐Center Study

Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Purpose This study aimed to evaluate the pregnancy outcomes of frozen embryo transfer (FET) in patients with persistent chronic endometritis (PCE). Methods 186 patients were stratified into three groups: Cured CE (CCE), Cured Persistent CE (CPCE), and Still Persistent CE (SPCE). Only the first post‐treatment FET cycle per patient was analyzed.
Yihua Liang, Zhaoyue Huang, Haiyan Lin, Qi Qiu, Xuedan Jiao, Qingxue Zhang   +5 more
wiley   +1 more source

Preconception One‐Carbon Metabolism Nutrient Levels in Preparing for Pregnancy Couples and Spontaneous Pregnancy Loss: A Prospective Cohort Study

MedComm, Volume 7, Issue 4, April 2026.
One‐carbon metabolism (OCM) nutrients play a critical role in fetal development and are implicated in the etiology of spontaneous pregnancy loss (SPL). In our large cohort study, we report for the first time that paternal red blood cell folate levels ≥ 400 ng/mL—consistent with the World Health Organization's recommendation for neural tube defect ...
Xiaotian Chen, Yi Zhang, Qing Yang, Hong Zhu, Jianwei Hu, Jian Huang, Longmei Jin, Xiaohua Zhang, Yalan Dou, Wennan He, Yuanchen He, Hongyan Chen, Qinyu Yao, Yuanzhou Peng, Xiaojing Ma, Wei Sheng, Guoying Huang, Weili Yan, the SPCC group   +18 more
wiley   +1 more source

A retrospective study on IVF outcome in euthyroid patients with anti-thyroid antibodies: effects of levothyroxine, acetyl-salicylic acid and prednisolone adjuvant treatments [PDF]

, 2009
Background Anti-thyroid antibodies (ATA), even if not associated with thyroid dysfunction, are suspected to cause poorer outcome of in vitro fertilization (IVF). Methods We retrospectively analyzed: (a) the prevalence of ATA in euthyroid infertile women,
Alberto Revelli, Simona Casano, Luisa Delle Piane, Giuseppina Grassi, Gianluca Gennarelli, Daniela Guidetti, Marco Massobrio, K Poppe, K Poppe, K Poppe, N Sinaii, L Belvisi, N Doldi, OE Janssen, H Orbach, S Bussen, CH Kim, AF Muller, S Kilic, WH Kutteh, K Poppe, R Negro, DY Aksoy, E Vaquero, WH Kutteh, I Hasegawa, E Geva, F Taniguchi, A Revelli, MF Prummel, WB Nothnick, A Hoek, RL Kelkar, OV Lastra, E Geva, A Singh, CB Tempfer, B Urman, N Lédée-Bataille, de Fried E Polak   +39 more
core   +1 more source

A Genetic Landscape of Euploid Miscarriages From Couples With Recurrent Pregnancy Loss Through Whole Exome Sequencing

Molecular Genetics &Genomic Medicine, Volume 14, Issue 4, April 2026.
Whole exome sequencing analysis on 55 couples and miscarriages from their current pregnancies reveals a significant heterogeneity and complexity in exomic variants contributing to RPL. ABSTRACT Background This study aimed to identify candidate genes for recurrent pregnancy loss (RPL).
Fanjuan Kong, Zhaochu Yin, Haiyan Zhou, Zhiyu Liu, Wanqin Xie   +4 more
wiley   +1 more source