Discovery of Oxyacanthine Dihydrochloride Monohydrate Polymorphs from Obfuscated Samples by Microcrystal Electron Diffraction. [PDF]
The practical application of microcrystal electron diffraction is demonstrated to identify two polymorphic crystal structures of oxyacanthine dihydrochloride monohydrate from obfuscated samples that had been mislabeled as "berbamine dihydrochloride".
Lin J, Paz O, Unge J, Gonen T.
europepmc +2 more sources
Rapid Structural Analysis of Natural Products Using MicroED. [PDF]
The cryoEM method, MicroED used for rapid analysis and structure determination of natural products that remained unattainable by other structural biology methods ABSTRACT Structural analysis of natural products remains challenging due to their inherent complexity and limited availability.
Lin J, Paz O, Unge J, Gonen T.
europepmc +2 more sources
With an increasing number of refined MicroED structures available to the community, lessons can be learned of their profiles and quality, as well as of best practices.As the electron diffraction technique MicroED gains momentum and is increasingly embraced by researchers in both academia and industry, we have the opportunity to familiarize ourselves ...
Unge J, Nannenga B, Oliver A, Gonen T.
europepmc +3 more sources
Minimally Invasive Intraoperative Laser Vibrometry (MIVIB)-A Peroperative Method to Measure Fixation of the Ossicular Chain. [PDF]
An objective assessment of the ossicular chain with laser vibrometry would likely improve the result of ossiculoplasty. MIVIB provides an objective assessment of the ossicular chain to identify specific fixations and therefore assist the surgeon in improving surgical outcomes. ABSTRACT Background Conductive hearing loss requires the surgeon to evaluate
Wales J +6 more
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Clinical Trial: Dose-Finding Study of Linaprazan Glurate, A Novel Potassium-Competitive Acid Blocker, Versus Lansoprazole for the Treatment of Erosive Oesophagitis. [PDF]
Linaprazan glurate achieved a 4‐week healing rate of 71.1% in the intention‐to‐treat (ITT) analysis and 80.9% in the per protocol set (PPS) analysis. In comparison, lansoprazole achieved healing rates of 60.6% (ITT) and 59.1% (PPS). ABSTRACT Background Linaprazan glurate, a potassium‐competitive acid blocker, is in development for the treatment of ...
Sharma P +9 more
europepmc +2 more sources
Unlocking Enhanced Efficacy of Aminoglycoside Antibiotics Against Pseudomonas aeruginosa. [PDF]
This opinion article reviews the use and challenges of aminoglycosides on the Gram‐negative pathogen Pseudomonas aeruginosa and highlights recent discoveries of adjuvants and/or other compounds that potentiate the activity of these antibiotics. ABSTRACT Infectious diseases continue to be a global health burden.
Tawiah PO, Sultana S, Dahl JU.
europepmc +2 more sources
Måleegenskaper ved den norske versjonen av Sense of Coherence (SOC-13)
Beskrivelse: Sense of Coherence (SOC)/Opplevelse av sammenheng ble utviklet av Antonovsky (1987) og består i originalversjonene av 29 spørsmål (SOC-29) og i en forkortet versjon av 13 spørsmål (SOC-13).
Sabine Kaiser, Henriette Kyrrestad
doaj +1 more source
Hvordan relasjonen mellom rettigheter og plikter erfares av ulike klientgrupper i velferdsstaten, er i liten grad studert. I lys av Frasers begrep om behovspolitikk, og hennes diskusjon om forholdet mellom behov og rettigheter, tar vi utgangspunkt i en ...
Heidi Moen Gjersøe +1 more
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Måleegenskaper ved den norske versjonen av Resilience Scale for Adolescents (READ)
Beskrivelse: Resilience Scale for Adolescents (READ) er et selvrapport spørreskjema for ungdom som måler resiliens; evnen til å håndtere stress og negative livshendelser.
Kristin Gärtner Askeland +1 more
doaj +1 more source
Semi-automated MicroED system unveils multiple polymorphs in fish-derived guanine crystals. [PDF]
A semi‐automated MicroED data collection and processing system was established and shown to be suitable for the structural investigation of submicrometer‐scale biogenic crystals.Certain fish display silvery or blue colour, not through pigments, but through specialized guanine crystals that exist within iridophore cells in their skin. Within these cells,
Nakazawa M +6 more
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