Results 51 to 60 of about 795,738 (197)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Inteligencia emocional y procrastinación académica en estudiantes universitarios en Perú

Ciencias Psicológicas
El objetivo de este estudio fue analizar la relación entre la Inteligencia Emocional (IE) y la Procrastinación Académica (PA) en estudiantes universitarios y generar un modelo predictivo. Este estudio tiene un enfoque cuantitativo y de diseño predictivo
Samuel Chavez-Fernandez, Yeniffer M. Haro-Rodriguez, Lucero G. Machaca-Calcina, Cristian E. Adriano Rengifo   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Fusiones / Adquisiciones y Acuerdos de Cooperación en la Unión Europea durante el periodo 2000-2007

Revista Galega de Economía, 2014
La realización de fusiones/adquisiciones y de acuerdos de cooperación dentro del marco europeo ha sido creciente a lo largo del siglo pasado. Sin embargo, la llegada del nuevo siglo nos muestra algunos cambios en las tendencias. El objetivo de este trabajo es analizar de forma descriptiva las características y evolución de las fusiones ...
openaire   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Simón Bolívar y José Martí: analogía en un pensamiento por la Unión Americana

Política Internacional, 2019
Revelar la ideología del imperativo de la unión para alcanzar la verdadera emancipación, garantizar mediante ella la protección y amparo de Las Antillas y Latinoamérica y enfrentar el ascendente interés norteamericano de instalarse y posesionarse de ...
Aíxa Cristina Kindelán Larrea
doaj  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

GEOGRAFÍAS INMATERIALES Y ARQUEOLOGÍA CONTEMPORÁNEA. PAISAJE, IDENTIDAD Y MEMORIA EN LA SIERRA MINERA DE CARTAGENA-LA UNIÓN (MURCIA)

, 2020
En este trabajo hemos querido mostrar la historia y el estado actual de la Arqueología Contemporánea. Nos hemos centrado en el principal objeto de estudio de esta disciplina (la sociedad contemporánea) mediante el rico paisaje cultural que ha sido generado y que aún hoy pervive en los edificios, las infraestructuras, las maquinas, los paisajes ...
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source