Results 71 to 80 of about 802,813 (248)

Evaluación de las propiedades físicas y mecánicas de ladrillos elaborados con lodos residuales de plantas de tratamiento de agua potable y aguas residuales

Gaceta Técnica
En esta investigación se tuvo como objetivo evaluar las propiedades físicas y mecánicas de ladrillos utilizando lodos residuales provenientes de plantas de tratamiento de agua potable y de tratamiento de aguas residuales.
Nicool Betsabe Orostegui Melendrez, Ingri Tatiana Godos Malca, Leonel Chahuares Paucar   +2 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Ratios de solvencia financiera y su influencia la rentabilidad: un análisis con regresión lineal de la empresa LAIVE S.A. entre 2018 y 2023

Revista Visión Contable
La presente investigación determinó los ratios de solvencia financiera y su influencia en la rentabilidad de LAIVE S.A., una empresa peruana del sector alimentario.
Evelyn Malpartida Clemente, Helmer Clemente Aviles, Oscar Eliel Chilón Ayay   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

New Predictors of Future Expectations in Peruvian University Students: A Study Conducted in Post-Pandemic Times

Psiquemag
The health crisis had negative repercussions on the university experience. Therefore, the aim was to determine if satisfaction with studies, academic self-efficacy, and emotional intelligence predict future expectations in Peruvian university students ...
Daniel David Calizaya-Rios, Evelyn Doris Mamani Quispe, Lizbeth Lidia Ylachoque Aquima, Liset Z. Sairitupa-Sanchez, Oscar Mamani-Benito   +4 more
doaj   +1 more source

Estimación del caudal a partir de la técnica de velocimetría por imágenes de partículas a gran escala aplicado en flujo a superficie libre

Gaceta Técnica, 2021
Este estudio tiene como objetivo estimar el caudal a partir de la técnica de velocimetría por Imágenes de Partículas a Gran Escala en flujo a superficie libre.
Fredy Sandro Rosas Flores, Shirley Pamela Tejeda Flores, Ferrer Canaza Rojas   +2 more
doaj  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Design and validation of the brand personality scale in food industries

Frontiers in Communication
In the competitive context in which food industries operate, the brand plays a predominant role in differentiating and establishing an emotional connection with customers.
Joel Cruz-Tarrillo, Jazmin Inaguazo, Clara Rodriguez-Rosales, José Tarrillo-Paredes, Jose E. Paz-Vilchez   +4 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source