Results 41 to 50 of about 988,602 (306)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

La educación y la formación permanentes: un reto para cada ciudadano

Revista Española de Pedagogía
The European Year devoted to education and lifelong learning is intended to be one more step towards public awareness of the relevance of education and lifelong learning not only to Europe but also to every European citizen.
Edith Cresson
doaj   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Participación argentina en inspecciones antárticas: ¿actividades esporádicas o ejercicios regulares

Cuadernos de Política Exterior Argentina, 2023
El objetivo de este trabajo es poder ofrecer una mirada estadística, comparativa e histórica, sobre la participación argentina en inspecciones del Sistema del Tratado Antártico, la importancia de haber alcanzado regularidad en su realización, así como ...
Rodrigo Conde Garrido
doaj  

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source

VI Cumbre Unión Europea-América Latina

Aportes para la Integración Latinoamericana, 2017
VI Cumbre Unión Europea-América Latína Declaración de Madrid. Madrid, España, 18 de mayo de 2010. Plan de Acción de Madrid 2010-2012 . Madrid, España, 18 de mayo de 2010.
Cumbre Union Europea América Latina
doaj  

Enhanced Oxidation and Thermal Shock Resistance of N‐type Mg2Si0.89(Sn0.1,Sb0.01) Thermoelectric Material via Cr0.9Si0.1 Coating

Advanced Engineering Materials, EarlyView.
Cr0.9Si0.1 protective coatings are developed to enhance the thermal‐shock and oxidation resistance of Mg2Si0.89(Sn0.1,Sb0.01) thermoelectric (TE) materials. The coating forms a dense and adherent barrier that suppresses oxygen diffusion and mitigates mechanical degradation during cyclic oxidation, demonstrating its potential to improve the long‐term ...
Mikdat Gurtaran, Zhenxue Zhang, Xiaoying Li, Hanshan Dong   +3 more
wiley   +1 more source

Dual‐Mode Film Based on Highly Scattering Nanofibers and Upcycled Chips‐Bags for Year‐Round Thermal Management

Advanced Functional Materials, EarlyView.
Intelligent radiative cooling devices, adaptable to various weather conditions, have the potential for year‐round energy savings. This study introduces a sustainable dual‐mode film made from polycaprolactone nanofibers and upcycled chip bags for effective thermal management.
Qimeng Song, Stefan Rettinger, Chengzhang Xu, Ulrich Mansfeld, Markus Retsch   +4 more
wiley   +1 more source