Results 151 to 160 of about 401,393 (281)

UDBMS: Road to Unification for Multi-model Data Management

, 2018
Jiaheng Lu, Zhen Hua Liu, Pengfei Xu, Chao Zhang   +3 more
openalex   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Higgs-lepton unification in $\mathrm{E}_8$-inspired supersymmetric trinification [PDF]

, 2016
José Eliel Camargo-Molina, A. Morais, Astrid Ordell, Roman Pasechnik, Marco O. P. Sampaio, Jonas Wessén   +5 more
openalex  

Particle Physics Models of Inflation in Supergravity and Grand Unification [PDF]

, 2010
P. Kostka
openalex   +1 more source

Towards Grand Unification

Sidharth had shown that gravitation can be reconciled with electromagnetic and other forces if we start from a Landau-Ginzburg phase transition. This is further remarked upon and a unification of all forces of nature is proposed.Comment: 10 pages, IIAMIS-
Sidharth, Burra G.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EDUCATIONAL INSTITUTION ADMINISTRATION AUTOMATION BASED ON ONTOLOGICAL MODELING AND SERVICE-ORIENTED ARCHITECTURE

Вестник Донского государственного технического университета, 2018
The current state of the national universities automation is touched upon. Some aspects of the automation being the key ones in building the information control system (ICS) are defined.
Andrey Alexandrovich Petrikin, Igor Vladimirovich Boguslavskiy   +1 more
doaj  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Evaluating voter perceptions of political party similarity: A mixed-method study of party positions in Taiwan. [PDF]

PLoS One
Chang SC.
europepmc   +1 more source