Results 141 to 150 of about 99,447 (295)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

The political and socio-economic challenges of Korean unification Lessons from Germany's post-unification experience

open access: yes, 1997
Das Heft enthaelt die deutschen Beitraege einer Konferenz, welche von der Seoul National University/ Korea und der Freien Universitaet Berlin veranstaltet wurde.
Freie Universitaet Berlin, FB Politische Wissenschaft, Institut fuer Internationale Politik und Regionalstudien WE 04, Berlin (Germany)   +1 more
core  

Why they persist? An analysis of dual class structures and the unification process in the U.S. and Brazil

open access: yesRevista Direito GV, 2014
The unbundling of cash flow and voting rights has been severely criticized worldwide and yet, the dual class structure persists as an alternative widely adopted by firms.
Gabriela M. Engler Pinto
doaj  

Ré-unification.

open access: yes, 2004
Dans sa graphie ordinaire, sans trait d’union, ce mot semble simple : il signifie le rétablissement d’une unité provisoirement rompue. L’idée sous-jacente est celle d’un retour à la normale, à un ordre indûment perturbé. La réunification allemande de 1990 annulait le découpage en deux États de 1949 pour revenir aux frontières de 1945.
openaire   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Educational attainment and first births: East Germany before and after unification [PDF]

open access: yes
There is a general belief that female educational attainment has a delaying effect on the age at first birth. In this paper we argue that the validity of this hypothesis relies on at least three prerequisites.
Michaela Kreyenfeld
core  

Bidirectional portal vein reconstruction for type C anatomy in living donor liver transplant. [PDF]

open access: yesTranspl Int
Shams-Ud-Din   +5 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

The power of theory in the life sciences. [PDF]

open access: yesElife
Fine JL   +4 more
europepmc   +1 more source

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